The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

Conspectus The Passerini three-component (P-3CR) and the Ugi four-component (U-4CR)
are two of the most prominent isocyanide-based multicomponent reactions (IMCRs). The P …

Oxazols neue Welt: Gold‐katalysierte intermolekulare Reaktionen von Pyridin‐N‐aminiden
mit Inamiden führen zu trisubstituierten 1, 3‐Oxazolen mit einer Vielzahl von funktionellen …

A collection of smart multicomponent reactions (MCRs) with continuative post condensation
cyclizations (PCCs) is presented to construct conventional three-to seven-membered …

A gold-catalyzed regioselective [3+ 2] cycloaddition of ynamides with 1, 4, 2-dioxazoles was
developed and offers a novel approach to obtain highly functionalized oxazoles under mild …

Reaction of isonitriles with 3‐(arylamino) isobenzofuran‐1 (3H)‐ones in the presence of a
catalytic amount of an octahydro (R)‐binol‐derived chiral phosphoric acid afforded 3‐oxo‐2 …

Thomas Buyck, Qian Wang, and Jieping Zhu* α-Isocyanoacetates are well-known glycine
templates for the synthesis of racemic α, α-disubstituted α-amino acids.[1] However, catalytic …

Presented herein is a new complexity‐generating method in which both functionalities of α‐
imino esters undergo stereoselective cyclization with isocyanoacetates to produce directly …

The α-alkylation of imines is a valuable carbon-carbon bondforming strategy which is still an
underdeveloped area,[1-3] despite the synthetic potential of its α-branched imine products. 4 …

Abstract Background Pyrazoles, thiazoles and 1, 3, 4-thiadiazoles have been reported to
possess various pharmacological activities. Results An efficient and a novel approach for …