Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies
BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …
Ceramides as mediators of oxidative stress and inflammation in cardiometabolic disease
M Gaggini, R Ndreu, E Michelucci… - International Journal of …, 2022 - mdpi.com
Ceramides, composed of a sphingosine and a fatty acid, are bioactive lipid molecules
involved in many key cellular pathways (eg, apoptosis, oxidative stress and inflammation) …
involved in many key cellular pathways (eg, apoptosis, oxidative stress and inflammation) …
Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort …
Objective Tryptophan can be catabolised to various metabolites through host kynurenine
and microbial indole pathways. We aimed to examine relationships of host and microbial …
and microbial indole pathways. We aimed to examine relationships of host and microbial …
Role of ceramides in the pathogenesis of diabetes mellitus and its complications
Diabetes mellitus (DM) is a systemic metabolic disease that affects 463 million adults
worldwide and is a leading cause of cardiovascular disease, blindness, nephropathy …
worldwide and is a leading cause of cardiovascular disease, blindness, nephropathy …
Menopause is associated with an altered gut microbiome and estrobolome, with implications for adverse cardiometabolic risk in the hispanic community health study …
Menopause is a pivotal period during which loss of ovarian hormones increases
cardiometabolic risk and may also influence the gut microbiome. However, the menopause …
cardiometabolic risk and may also influence the gut microbiome. However, the menopause …
Very long-chain saturated fatty acids and diabetes and cardiovascular disease
RN Lemaitre, IB King - Current opinion in lipidology, 2022 - journals.lww.com
Very long-chain saturated fatty acids and diabetes and cardi... : Current Opinion in Lipidology
Very long-chain saturated fatty acids and diabetes and cardiovascular disease : Current …
Very long-chain saturated fatty acids and diabetes and cardiovascular disease : Current …
Machine learning approaches reveal metabolic signatures of incident chronic kidney disease in individuals with prediabetes and type 2 diabetes
Early and precise identification of individuals with prediabetes and type 2 diabetes (T2D) at
risk for progressing to chronic kidney disease (CKD) is essential to prevent complications of …
risk for progressing to chronic kidney disease (CKD) is essential to prevent complications of …
Association of the gut microbiome with kidney function and damage in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Background The gut microbiome is altered in chronic kidney disease (CKD), potentially
contributing to CKD progression and co-morbidities, but population-based studies of the gut …
contributing to CKD progression and co-morbidities, but population-based studies of the gut …
Healthful eating patterns, serum metabolite profile and risk of diabetes in a population-based prospective study of US Hispanics/Latinos
Aims/hypothesis We aimed to evaluate associations of multiple recommended dietary
patterns (ie the alternate Mediterranean diet [aMED], the Healthy Eating Index [HEI]-2015 …
patterns (ie the alternate Mediterranean diet [aMED], the Healthy Eating Index [HEI]-2015 …
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes
Aims/hypothesis Emerging evidence suggests that in addition to hyperglycaemia,
dyslipidaemia could represent a contributing pathogenetic factor to diabetic neuropathy …
dyslipidaemia could represent a contributing pathogenetic factor to diabetic neuropathy …