Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium

J Dey, SR Mahapatra, TK Raj, T Kaur, P Jain, A Tiwari… - Gut Pathogens, 2022 - Springer
Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe
public health complications in humans. There are currently no licensed treatments or …

Refining the DC-targeting vaccination for preventing emerging infectious diseases

Y Pastor, N Ghazzaui, A Hammoudi… - Frontiers in …, 2022 - frontiersin.org
The development of safe, long-term, effective vaccines is still a challenge for many infectious
diseases. Thus, the search of new vaccine strategies and production platforms that allow …

Identification of potential novel B-cell epitopes of capsid protein VP2 in Senecavirus A

Y Ru, R Hao, C Wu, Y Li, B Lu, H Liu, H Tian… - Microbiology …, 2023 - Am Soc Microbiol
Senecavirus A (SVA) is a type of nonenveloped single-stranded, positive-sense RNA virus.
The VP2 protein is a structural protein that plays an important role in inducing early and late …

Putative new combination vaccine candidates identified by reverse vaccinology and genomic approaches to control enteric pathogens

S Mikaeel, A Doosti, A Sharifzadeh - BMC immunology, 2024 - Springer
Objectives The pathogenic microorganisms that cause intestinal diseases can significantly
jeopardize people's health. Currently, there are no authorized treatments or vaccinations …

Humoral and cellular immunity in response to an in silico-designed multi-epitope recombinant protein of Theileria annulata

A Abid, A Khalid, M Suleman, H Akbar… - Frontiers in …, 2024 - frontiersin.org
Tropical theileriosis is a lymphoproliferative disease caused by Theileria annulata and is
transmitted by Ixodid ticks of the genus Hyalomma. It causes significant losses in livestock …

In silico designed Staphylococcus aureus B-cell multi-epitope vaccine did not elicit antibodies against target antigens suggesting multi-domain approach

N Ullah, F Anwer, Z Ishaq, A Siddique, MA Shah… - Journal of …, 2022 - Elsevier
The vaccine development strategies have evolved from using an entire organism as an
immunogen to a single antigen and further towards an epitope. Since an epitope is a …

Molecular characterization of Anaplasma ovis Msp4 protein in strains isolated from ticks in Turkey: A multi-epitope synthetic vaccine antigen design against …

AE Köseoğlu, H Can, M Güvendi, SE Alak, AD Döşkaya… - Biologicals, 2024 - Elsevier
Tick-borne pathogens increasingly threaten animal and human health as well as cause
great economic loss in the livestock industry. Among these pathogens, Anaplasma ovis …

Design and evaluation of a multi-epitope vaccine for COVID-19: an in silico approach

M Tourani, S Samavarchi Tehrani… - Health Science …, 2023 - hsm.umsu.ac.ir
Background & Aims: Corona virus disease-19 (COVID-19) is an evolving global disease
which has burst into 2019. SARS-CoV-2 infects human cells through recognition of and …