Significance testing of synergistic/antagonistic, dose level‐dependent, or dose ratio‐dependent effects in mixture dose‐response analysis
MJ Jonker, C Svendsen, JJM Bedaux… - … and Chemistry: An …, 2005 - Wiley Online Library
In ecotoxicology, the state of the art for effect assessment of chemical mixtures is through
multiple dose—response analysis of single compounds and their combinations …
multiple dose—response analysis of single compounds and their combinations …
[图书][B] Joint toxic effects on Caenorhabditis elegans on the analysis and interpretation of mixture toxicity data
MJ Jonker - 2003 - search.proquest.com
In polluted areas organisms are generally exposed to mixtures of toxic chemicals rather than
a single toxicant only. Since the number of mixture toxicity studies with regard to soil systems …
a single toxicant only. Since the number of mixture toxicity studies with regard to soil systems …
Drug–Drug Pharmacodynamic Interaction Detection by a Nonparametric Population Approach. Influence of Design and of Interindividual Variability
Y Merlé, A Mallet, E Schmautz - Journal of pharmacokinetics and …, 1999 - Springer
Population approaches are appealing methods for detecting then assessing drug–drug
interactions mainly because they can cope with sparse data and quantify the interindividual …
interactions mainly because they can cope with sparse data and quantify the interindividual …