Adolescent alcohol exposure persistently impacts adult neurobiology and behavior

FT Crews, RP Vetreno, MA Broadwater… - Pharmacological …, 2016 - ASPET
Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

Mechanisms of neurodegeneration and regeneration in alcoholism

FT Crews, K Nixon - Alcohol & Alcoholism, 2009 - academic.oup.com
Aims: This is a review of preclinical studies covering alcohol-induced brain neuronal death
and loss of neurogenesis as well as abstinence-induced brain cell genesis, eg brain …

Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates

TD Perera, JD Coplan, SH Lisanby… - Journal of …, 2007 - Soc Neuroscience
New neurons are generated in the adult hippocampus of many species including rodents,
monkeys, and humans. Conditions associated with major depression, such as social stress …

Hippocampal adult neurogenesis: Its regulation and potential role in spatial learning and memory

C Lieberwirth, Y Pan, Y Liu, Z Zhang, Z Wang - Brain research, 2016 - Elsevier
Adult neurogenesis, defined here as progenitor cell division generating functionally
integrated neurons in the adult brain, occurs within the hippocampus of numerous …

[HTML][HTML] Binge ethanol exposure during adolescence leads to a persistent loss of neurogenesis in the dorsal and ventral hippocampus that is associated with impaired …

RP Vetreno, FT Crews - Frontiers in neuroscience, 2015 - frontiersin.org
Adolescence is a developmental period that coincides with the maturation of adult cognitive
faculties. Binge drinking is common during adolescence and can impact brain maturation …

[HTML][HTML] Impact of diet on adult hippocampal neurogenesis

D Stangl, S Thuret - Genes & nutrition, 2009 - Springer
Research over the last 5 years has firmly established that learning and memory abilities, as
well as mood, can be influenced by diet, although the mechanisms by which diet modulates …

Neurogenesis in adolescent brain is potently inhibited by ethanol

FT Crews, A Mdzinarishvili, D Kim, J He, K Nixon - Neuroscience, 2006 - Elsevier
Adolescence is a period of progressive changes in brain that likely contribute to the
maturation of behavior. Human adolescents consume large amounts of ethanol. To …

Neuroimmune basis of alcoholic brain damage

FT Crews, RP Vetreno - International review of neurobiology, 2014 - Elsevier
Alcohol-induced brain damage likely contributes to the dysfunctional poor decisions
associated with alcohol dependence. Human alcoholics have a global loss of brain volume …

Determination of key aspects of precursor cell proliferation, cell cycle length and kinetics in the adult mouse subgranular zone

CD Mandyam, GC Harburg, AJ Eisch - Neuroscience, 2007 - Elsevier
Neurogenesis studies on the adult mouse hippocampal subgranular zone (SGZ) typically
report increases or decreases in proliferation. However, key information is lacking about …

Alcohol inhibition of neurogenesis: a mechanism of hippocampal neurodegeneration in an adolescent alcohol abuse model

SA Morris, DW Eaves, AR Smith, K Nixon - Hippocampus, 2010 - Wiley Online Library
Adolescents diagnosed with an alcohol use disorder show neurodegeneration in the
hippocampus, a region important for learning, memory, and mood regulation. This study …