Achieving sufficient delivery across the blood–brain barrier is a key challenge in the
development of drugs to treat central nervous system (CNS) disorders. This is particularly …

The aim of this review is to give an outline of the blood clearance function of the liver
sinusoidal endothelial cells (LSECs) in health and disease. Lining the hundreds of millions …

The present AST‐IDCOP guidelines update information on BK polyomavirus (BKP yV)
infection, replication, and disease, which impact kidney transplantation (KT), but rarely non …

The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic
sinusoid and functions as a control post regulating and surveying the trafficking of molecules …

This update focuses on two main topics. First, recent developments in our understanding of
liver sinusoidal endothelial cell (LSEC) function will be reviewed, specifically elimination of …

Abstract 'Angiodiversity'refers to the structural and functional heterogeneity of endothelial
cells (EC) along the segments of the vascular tree and especially within the microvascular …

BK polyomavirus (BKPyV) replication causes nephropathy and premature kidney transplant
failure. Insufficient BKPyV-specific T cell control is regarded as a key mechanism, but direct …

Lipopolysaccharide (LPS) in blood circulation causes endotoxemia and is linked to various
disease conditions. Current treatments focus on preventing LPS from interacting with its …

Liver sinusoidal endothelial cells (LSECs) present unique, highly specialised endothelial
cells in the body. Unlike the structure and function of typical, vascular endothelial cells …

The liver is constantly exposed to dietary antigens, viruses, and bacterial products with
inflammatory potential. For decades cellular uptake of virus has been studied in connection …