Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the
effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in …

The barrier surfaces of the gastrointestinal tract are in constant contact with various
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …

Our understanding of protective versus pathological immune responses to SARS-CoV-2, the
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …

Simple Summary Hepatocellular carcinoma (HCC) constitutes a major health burden,
accounting for> 80% of primary liver cancers globally. Inflammation has come into the …

Immune cell–based therapies are promising strategies to facilitate immunosuppression
withdrawal after organ transplantation. Regulatory dendritic cells (DCreg) are innate …

Myeloid-derived suppressor cells (MDSCs) are cells of myeloid lineage with a potent
immunosuppressive capacity. They are present in cancer patients as well as in patients with …

Dendritic cells (DCs) are well-established as major players in the regulation of immune
responses. They either induce inflammatory or tolerogenic responses, depending on the DC …

Tolerogenic dendritic cells play a critical role in promoting antigen-specific tolerance via
dampening of T cell responses, induction of pathogenic T cell exhaustion and antigen …

Dendritic cells (DCs) dictate the outcomes of tissue-specific immune responses. In the
context of autoimmune diseases, DCs instruct T cells to respond to antigens (Ags), including …

Osteosarcoma is a malignant primary bone tumor commonly occurring in children and
adolescents. The treatment of local osteosarcoma is mainly based on surgical resection and …