Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

In patients with severe or critical Coronavirus disease 2019 (COVID-19) manifestations, a
thromboinflammatory syndrome, with diffuse microvascular thrombosis, is increasingly …

The dependence of development and homeostasis in animals on the interaction of hundreds
of extracellular regulatory proteins with the peri-and extracellular glycosaminoglycan …

Many pathogens take advantage of the dependence of the host on the interaction of
hundreds of extracellular proteins with the glycosaminoglycans heparan sulphate to …

Heparin and heparan sulfate glycosaminoglycans are long, linear polysaccharides that are
made up of alternating dissacharide sequences of sulfated uronic acid and amino sugars …

Abstract Coronavirus Disease 2019 (COVID-19) pandemic has been on the agenda of
humanity for more than 2 years. In the meantime, the pandemic has caused economic …

Our objective is to reveal the molecular mechanism of the anti-inflammatory action of low-
molecular-weight heparin (LMWH) based on its influence on the activity of two key cytokines …

Adenovirus pneumonia is common in pediatric upper respiratory tract infection, which is
comparatively easy to develop into severe cases and has a high mortality rate with many …

The recent Zika virus (ZIKV) outbreak, which mainly affected Brazil and neighbouring states,
demonstrated the paucity of information concerning the epidemiology of several flaviruses …

Heparin, the widely used pharmaceutical anticoagulant, has been in clinical use for well
over half a century. Its introduction reduced clotting risks substantially and subsequent …