BR Luce, JM Kramer, SN Goodman… - Annals of internal …, 2009 - acpjournals.org
This companion article to Sox and Greenfield's report describes better research methods for CER. It addresses the fundamental limitations of traditional randomized, controlled trials for …
SW Glickman, JG McHutchison, ED Peterson… - N Engl J …, 2009 - researchgate.net
Ethical and Scientific Implications of the Globalization of Clinical Research Page 1 sounding board The new england journal of medicine n engl j med 360;8 nejm.org february 19, 2009 …
Until the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic …
The hypothesis that ablative therapies (such as surgery or radiation) can be used to cure patients with a limited number of metastases was influential in changing practice. Early …
The National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies. However, the program is …
I am incredibly fortunate. To receive an award from the Lasker Foundation, with its preeminent jury, is indeed an honor. But the greatest reward is seeing patients every week …
SK Cheng, MS Dietrich, DM Dilts - Clinical Cancer Research, 2010 - AACR
Purpose: Postactivation barriers to oncology clinical trial accruals are well documented; however, potential barriers prior to trial opening are not. We investigate one such barrier …
AT Schroen, GR Petroni, H Wang, R Gray… - Clinical …, 2010 - journals.sagepub.com
Background A major challenge for randomized phase III oncology trials is the frequent low rates of patient enrollment, resulting in high rates of premature closure due to insufficient …
DJ Stewart, SN Whitney, R Kurzrock - Journal of clinical oncology, 2010 - ascopubs.org
Cancer is the leading cause of death in Americans younger than 85 years of age and kills one American every 56 seconds. Advances in understanding of cancer biology have given …