Development and Treatments of Inflammatory Cells and Cytokines in Spinal Cord Ischemia‐Reperfusion Injury

P Zhu, J Li, M Fujino, J Zhuang… - Mediators of inflammation, 2013 - Wiley Online Library
During aortic surgery, interruption of spinal cord blood flow might cause spinal cord
ischemia‐reperfusion injury (IRI). The incidence of spinal cord IRI after aortic surgery is up to …

Exogenous hydrogen sulfide plays an important role through regulating autophagy in ischemia/reperfusion injury

S Lv, Z Wang, J Wang, H Wang - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Ischemia/reperfusion (I/R) injury is characterized by limiting blood supply to organs, then
restoring blood flow and reoxygenation. It leads to many diseases, including acute kidney …

Hydrogen sulfide protects spinal cord and induces autophagy via miR-30c in a rat model of spinal cord ischemia-reperfusion injury

L Li, H Jiang, Y Li, Y Guo - Journal of Biomedical Science, 2015 - Springer
Abstract Background Hydrogen sulfide (H2S), a novel gaseous mediator, has been
recognized as an important neuromodulator and neuroprotective agent in the nervous …

[HTML][HTML] Hydrogen sulfide upregulated lncRNA CasC7 to reduce neuronal cell apoptosis in spinal cord ischemia-reperfusion injury rat

Y Liu, L Pan, AO Jiang, M Yin - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Objective Hydrogen sulfide has been recognized as an important neuroprotective agent in
the nervous system. The present study aimed to study the effect and the underlying …

Protective effect of hydrogen-rich saline on spinal cord damage in rats

M Kayabaş, L Şahin, M Makav, D Alwazeer, L Aras… - Pharmaceuticals, 2023 - mdpi.com
The anti-inflammatory and anti-apoptotic effects of molecular hydrogen, delivered as
hydrogen-rich saline (HRS), on spinal cord injury was investigated. Four-month-old male …

Rehabilitation report of 2 cases of spinal cord ischemic injury after intra-aortic repair

S Cheng, X Li, Y Zhang, C Liu, Y Rao, Y Zhang, J Wu… - Medicine, 2024 - journals.lww.com
Interventions: The patients received strength and transfer training, sensory input, health
mission, and activities of daily living. Outcomes: Patient 1 returned home without assistive …

Continuous blood exchange in rats as a novel approach for experimental investigation

S Pei, Y Wang, Z Zhang, C Mei, W Yin, X Fu, D Yan… - Scientific Reports, 2024 - nature.com
Blood exchange therapy, specifically Whole blood exchange (WBE), is increasingly being
utilized in clinical settings to effectively treat a range of diseases. Consequently, there is an …

The neuroprotective mechanism of puerarin in the treatment of acute spinal ischemia–reperfusion injury is linked to cyclin-dependent kinase 5

F Tian, LH Xu, B Wang, LJ Tian, XL Ji - Neuroscience Letters, 2015 - Elsevier
Puerarin is shown to exert a variety of pharmacological effects including neuroprotective
properties. However, mechanisms of the action are not fully understood. This study was …

[HTML][HTML] Whole blood exchange ameliorates acute hemolytic anemia by reducing inflammation and oxidative stress in rats

S Pei, Y Wang, R Yao, Z Zhang, W Yin… - The FASEB …, 2025 - pmc.ncbi.nlm.nih.gov
Hemolytic anemia (HA) is characterized by massive destruction of red blood cells (RBCs)
and insufficient oxygen supply, which can lead to shock, organ failure, even death. Recent …

Adeno-associated virus packaged TRPC5 gene therapy alleviated spinal cord ischemic reperfusion injury in rats

N Shen, L Wang, Y Wu, Y Liu, H Pei, H Xiang - Neuroreport, 2020 - journals.lww.com
Spinal cord injury (SCI) is a devastating disease with few effective treatments. This study
mainly explored the mechanism of TRPC5 gene in the treatment of spinal cord ischemia …