Classical chemotherapeutic agents such as mitotic inhibitors (spindle poisons), alkylating
agents, antimetabolites, topoisomerase inhibitors, and anthracenediones (anthracyclines) …

Curcumin, a derivative from the dried rhizome of curcuma longa, has been proven to
possess anti-tumor effects. However, the detailed molecular mechanisms have not been …

The BCL2 family of proteins includes apoptosis-related molecules involved in normal
physiology, as well as cancer pathology. Members of our team have discovered and cloned …

Lung cancer is one of the most common types of cancer in men and women and a leading
cause of death worldwide resulting in more than one million deaths per year. The venom of …

Abstract BCL2-like 12 (BCL2L12) is a new member of the apoptosis-related BCL2 gene
family, members of which are implicated in various malignancies. Nasopharyngeal …

Background Nasopharyngeal carcinoma (NPC) is a highly metastatic epithelial malignancy
showing high prevalence in Southeast Asia and North Africa. The BCL2-associated X (BAX) …

Abstract MicroRNA (miR)-185, which has been reported to be abnormally expressed in
some types of cancer, exerts significant effects on the proliferation, apoptosis, drug …

Koelreuteria henryi Dummer, an endemic plant of Taiwan, has been used as a folk medicine
for the treatment of hepatitis, enteritis, cough, pharyngitis, allergy, hypertension …

In the past, we identified and cloned the BCL2-like 12 (BCL2L12) gene, a novel member of
the BCL2 family, which is implicated in various malignancies. The classical BCL2L12 protein …

This study investigated the interrelationship between Lycium barbarum (goji) and gene
expression in mouse spleen. Oligomicroarray technology was employed to explore the …