Alpha‐ketoglutarate (AKG) is a crucial intermediate of the Krebs cycle and plays a critical
role in multiple metabolic processes in animals and humans. Of note, AKG contributes to the …

An intermediate of tricarboxylic acid cycle alpha-ketoglutarate (AKG) is involved in
pleiotropic metabolic and regulatory pathways in the cell, including energy production …

Oxidative stress is a major stress type observed in yeast bioprocesses, resulting in a
decrease in yeast growth, viability, and productivity. Thus, robust yeast strains with …

This study investigated the glycinin and β-conglycinin induced intestinal damage and α-
ketoglutarate alleviating the damage of glycinin and β-conglycinin in intestine. Carp were …

Recently, α-ketoglutaric acid (AKG) has gained importance as an antioxidant. Its dietary
supplementation in animals and humans has proved beneficial. Moreover, an extensive …

α-Ketoglutarate (AKG) can act as an antioxidant both in vitro and in vivo. However, the
mechanisms of the protective effects of AKG are still not well understood. We evaluated the …

The central carbon metabolism of microbes will likely be used in future sustainable
bioproduction. A sufficiently deep understanding of central metabolism would advance the …

Platelets from patients with myeloproliferative neoplasms (MPNs) exhibit a hyperreactive
phenotype. Here, we found elevated P-selectin exposure and platelet-leukocyte aggregates …

Abstract Cycles of Cdc53/Cullin1 rubylation (aka NEDDylation) protect ubiquitin-E3 SCF
(Skp1-Cullin1-F-box protein) complexes from self-destruction and play an important role in …

Lipids are essential energy storage compounds and are the core structural elements of all
biological membranes. During wine alcoholic fermentation, the ability of yeasts to adjust the …