Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health

T Li, Z Wang, J Guo, C de la Fuente-Nunez… - Science of The Total …, 2023 - Elsevier
The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

Colistin: from the shadows to a One Health approach for addressing antimicrobial resistance

M Rhouma, JY Madec, R Laxminarayan - International Journal of …, 2023 - Elsevier
Antimicrobial resistance (AMR) poses a serious threat to human, animal and environmental
health worldwide. Colistin has regained importance as a last-resort treatment against multi …

Multitalented synthetic antimicrobial peptides and their antibacterial, antifungal and antiviral mechanisms

T Vanzolini, M Bruschi, AC Rinaldi, M Magnani… - International Journal of …, 2022 - mdpi.com
Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …

Polymyxin and lipopeptide antibiotics: membrane-targeting drugs of last resort

EVK Ledger, A Sabnis, AM Edwards - Microbiology, 2022 - microbiologyresearch.org
The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …

Plasmid-mediated transfer of antibiotic resistance genes in soil

M Meng, Y Li, H Yao - Antibiotics, 2022 - mdpi.com
Due to selective pressure from the widespread use of antibiotics, antibiotic resistance genes
(ARGs) are found in human hosts, plants, and animals and virtually all natural environments …

Resistance mechanisms in Gram-negative bacteria

JA Lepe, L Martínez-Martínez - Medicina Intensiva (English Edition), 2022 - Elsevier
Enterobacterales resistant to carbapenems or producing extended-spectrum β-lactamases
(ESBL) and non-fermenters resistant to carbapenems present resistance to many of the …

High prevalence of mgrB-mediated colistin resistance among carbapenem-resistant Klebsiella pneumoniae is associated with biofilm formation, and can be …

AMS Shein, DL Wannigama, PG Higgins, C Hurst… - Scientific Reports, 2022 - nature.com
The global prevalence of colistin-resistant Klebsiella pneumoniae (ColRkp) facilitated by
chromosomal and plasmid-mediated Ara4N or PEtN-remodeled LPS alterations has steadily …

Synergistic efficacy of colistin and silver nanoparticles impregnated human amniotic membrane in a burn wound infected rat model

N Wali, A Shabbir, N Wajid, N Abbas, SZH Naqvi - Scientific reports, 2022 - nature.com
Antimicrobials used to treat burn wound infections have become multidrug-resistant, thus
delaying wound healing. When combined with silver nanoparticles, antibiotics create a …

[HTML][HTML] Phage-mediated colistin resistance in Acinetobacter baumannii

M Lucidi, F Imperi, I Artuso, G Capecchi… - Drug Resistance …, 2024 - Elsevier
Aims Antimicrobial resistance is a global threat to human health, and Acinetobacter
baumannii is a paradigmatic example of how rapidly bacteria become resistant to clinically …

Next-generation polymyxin class of antibiotics: A ray of hope illuminating a dark road

AT Aslan, M Akova, DL Paterson - Antibiotics, 2022 - mdpi.com
Although new-generation antimicrobials, in particular β-lactam/β-lactamase inhibitors, have
largely replaced polymyxins in carbapenem-resistant Gram-negative bacterial infections …