Challenges for global antibiotic regimen planning and establishing antimicrobial resistance targets: implications for the WHO Essential Medicines List and AWaRe …

N Reza, A Gerada, KE Stott, A Howard… - Clinical Microbiology …, 2024 - Am Soc Microbiol
SUMMARY The World Health Organisation's 2022 AWaRe Book provides guidance for the
use of 39 antibiotics to treat 35 infections in primary healthcare and hospital facilities. We …

Addition of probenecid to oral β-lactam antibiotics: a systematic review and meta-analysis

RC Wilson, P Arkell, A Riezk, M Gilchrist… - Journal of …, 2022 - academic.oup.com
Objectives To explore the literature comparing the pharmacokinetic and clinical outcomes
from adding probenecid to oral β-lactams. Methods Medline and EMBASE were searched …

Frequency of pharmacological target attainment with flucloxacillin and cefazolin in invasive methicillin-susceptible Staphylococcus aureus infection: a prospective …

PO Campbell, PKL Chin, SC Dalton… - International Journal of …, 2023 - Elsevier
Background The proportion of patients with invasive methicillin-susceptible Staphylococcus
aureus (MSSA) infection who achieve target concentrations of flucloxacillin or cefazolin with …

Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue–Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations

K Öbrink-Hansen, AD Pham, M Bue, P Hanberg… - Pharmaceutical …, 2022 - Springer
Purpose Flucloxacillin is a β-lactam penicillin commonly used in the treatment of bone and
soft tissue infections. In a recent porcine study, we found surprisingly low time for which the …

Oral antimicrobial therapy for cellulitis versus outpatient parenteral antimicrobial therapy: a single‐centre audit of cellulitis outcomes

TR Bowhay, T Tsang, JCZ Wei, W Edwik… - Internal medicine …, 2024 - Wiley Online Library
Background Cellulitis is a common acute skin and soft tissue infection that causes
substantial morbidity and healthcare costs. Aims To audit the impact on cellulitis …

Demonstrating the health economic benefit of alternative management strategies: how emergency department initiated outpatient care of cellulitis can save healthcare …

M Than, T Love - Canadian Journal of Emergency Medicine, 2022 - Springer
In this edition of the journal, Yadav and colleagues describe original research comparing
cost differences for two different outpatient parenteral antibiotic therapy (OPAT) approaches …

[PDF][PDF] Farmakokinetické vlastnosti flukloxacilinu

V Kubíčková, V Vojtová, K Urbánek - Farmacie Pro Praxi, 2023 - klinickafarmakologie.cz
Flucloxacillin is a semi-synthetic betalactam antibiotic from the group of isoxazolylpenicillins.
It differs from oxacillin by the attachment of one fluorine-chlorine atom to the benzene …