Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation

SB Raut, PA Marathe, L van Eijk, R Eri… - Pharmacology & …, 2022 - Elsevier
Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

Effect of cannabis on memory consolidation, learning and retrieval and its current legal status in India: A review

N Niloy, TA Hediyal, C Vichitra, S Sonali… - Biomolecules, 2023 - mdpi.com
Cannabis is one of the oldest crops grown, traditionally held religious attachments in various
cultures for its medicinal use much before its introduction to Western medicine. Multiple …

The 'entourage effect'or 'hodge-podge hashish': The questionable rebranding, marketing, and expectations of cannabis polypharmacy

PS Cogan - Expert review of clinical pharmacology, 2020 - Taylor & Francis
Introduction The concept of a cannabis 'entourage effect'was first coined as a hypothetical
afterthought in 1998. Since then, multiple scientific reviews, lay articles, and marketing …

Effects of ∆9-tetrahydrocannabinol on aversive memories and anxiety: a review from human studies

AM Raymundi, TR Da Silva, JMB Sohn, LJ Bertoglio… - BMC psychiatry, 2020 - Springer
Background Posttraumatic stress disorder (PTSD) may stem from the formation of aberrant
and enduring aversive memories. Some PTSD patients have recreationally used Cannabis …

Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool

CMB Kwee, JMA van Gerven… - Journal of …, 2022 - journals.sagepub.com
Background: Preclinical research suggests that cannabidiol (CBD) may have therapeutic
potential in pathological anxiety. Dosing guidelines to inform future human studies are …

Medial prefrontal cortex mechanisms of cannabidiol-induced aversive memory reconsolidation impairments

H Bayer, CAJ Stern, F Troyner, L Gazarini… - …, 2022 - Elsevier
Growing evidence indicates that cannabidiol (CBD), a substance present in the Cannabis
sativa plant, has potential therapeutic value to regulate abnormal emotional memories …

Cannabidiol (CBD) reduces cocaine-environment memory in mice

R Chesworth, T Karl - Pharmacology Biochemistry and Behavior, 2020 - Elsevier
Rationale Cocaine addiction is a global health problem with no approved
pharmacotherapies. Preclinical research indicates the non-intoxicating phytocannabinoid …

Increased cannabis intake during the COVID-19 pandemic is associated with worsening of depression symptoms in people with PTSD

A Murkar, T Kendzerska, J Shlik, L Quilty, M Saad… - BMC psychiatry, 2022 - Springer
Background Some evidence suggests substance use affects clinical outcomes in people
with posttraumatic stress disorder (PTSD). However, more work is required to examine links …

Cannabidiol impairs fear memory reconsolidation in female rats through dorsal hippocampus CB1 but not CB2 receptor interaction

JM Franzen, F Vanz, I Werle, FS Guimarães… - European …, 2022 - Elsevier
Women present increased susceptibility to anxiety-and stress-related disorders compared to
men. A potentially promising pharmacological-based strategy to regulate abnormal aversive …

Use of Cannabidiol (CBD) oil in the treatment of PTSD: Study design and rationale for a placebo-controlled randomized clinical trial

MJ Telch, CM Fischer, ED Zaizar, M Rubin… - Contemporary clinical …, 2022 - Elsevier
Background The burden of illness for PTSD is staggering and confers significant
interference in work, social functioning, as well as increased risk for other physical and …