Radiation protection of sodium alginate and its regulatory effect on intestinal microflora in mice

Z Qiao, Z Li, Y Shi, J Yi, J Zhu, Q Kang, L Hao… - International Journal of …, 2024 - Elsevier
Prolonged or high-dose exposure to ionizing radiation (IR) can cause damage to normal
tissues of the body. Therefore, it is imperative to find effective radiation protective agents to …

[HTML][HTML] Pharmacological Ascorbate Combined with Rucosopasem Selectively Radio-chemo-sensitizes NSCLC via Generation of H2O2

CF Pulliam, MA Fath, S Sho, ST Johnson, BA Wagner… - Redox Biology, 2025 - Elsevier
Differences in cancer and normal cell oxidative metabolism provide a unique therapeutic
opportunity for developing combined modality approaches with redox-active small …

Thyroxine alleviates interstitial lung disease induced by combined radiotherapy and immunotherapy

Y Mo, Y Qin, P Li, M Wu, D Chen, J Yu - Cancer Letters, 2025 - Elsevier
Immune checkpoint blockade (ICB) combined with radiotherapy (RT) has improved patients
survival, but also increased the risk of pulmonary adverse effects (AEs). Therefore, to …

IL-17A's role in exacerbating radiation-induced lung injury: Autophagy impairment via the PP2A-mTOR pathway

L Liu, GM Yi, X Li, C Chen, K Chen, H He, J Li… - … et Biophysica Acta (BBA …, 2025 - Elsevier
Objective Radiation-induced lung injury (RILI) is a serious complication of radiotherapy, and
the role of IL-17A in this process is not well understood. While IL-17A has been shown to …

[HTML][HTML] MicroRNA-541-3p/Rac2 signaling bridges radiation-induced lung injury and repair

J Zhang, L Ma, L He, Q Xu, Y Ding, L Wang - Non-coding RNA Research, 2025 - Elsevier
Background While radiation-induced lung injury decreases quality of life and suppresses
efficacy of radiotherapy, to date, the relationship between radiation-induced lung injury and …

[HTML][HTML] ALDH2 attenuates radiation-induced lung injury by inhibiting ROS and epithelial-mesenchymal transition mediated by the TGF-β1/Smad pathway

E Li, J Huang, J Huang, F Zhang, C Li, M Xia… - Pulmonary …, 2024 - Elsevier
Radiation-induced lung injury is a significant complication of thoracic malignant tumor
radiotherapy, yet effective treatments remain scarce. Aldehyde dehydrogenase 2 (ALDH2) …

Single-cell transcriptomic analysis of radiation-induced lung injury in rat

XY Shi, YQ Zhu, CJ Liang, T Chen, Z Shi… - Biomolecules and …, 2024 - bjbms.org
Radiation-induced lung injury (RILI) frequently occurs as a complication following
radiotherapy for chest tumors like lung and breast cancers. However, the precise underlying …