Choroidal blood flow: review and potential explanation for the choroidal venous anatomy including the vortex vein system

RF Spaide - Retina, 2020 - journals.lww.com
Purpose: To review control mechanisms for blood flow in the choroid, propose a system by
which venous outflow is controlled by a Starling resistor, and propose an explanation for the …

Autophagy Activation Promoted by Pulses of Light and Phytochemicals Counteracting Oxidative Stress during Age-Related Macular Degeneration

R Pinelli, M Ferrucci, F Biagioni, C Berti, VV Bumah… - Antioxidants, 2023 - mdpi.com
The seminal role of autophagy during age-related macular degeneration (AMD) lies in the
clearance of a number of reactive oxidative species that generate dysfunctional …

Melatonin protects the retina from experimental nonexudative age‐related macular degeneration in mice

HH Diéguez, MF González Fleitas… - Journal of Pineal …, 2020 - Wiley Online Library
Nonexudative age‐related macular degeneration (NE‐AMD) represents the leading cause
of blindness in the elderly. Currently, there are no available treatments for NE‐AMD. We …

Oxidative stress damage circumscribed to the central temporal retinal pigment epithelium in early experimental non-exudative age-related macular degeneration

HH Dieguez, HE Romeo, A Alaimo, MFG Fleitas… - Free Radical Biology …, 2019 - Elsevier
Non-exudative age-related macular degeneration (NE-AMD) represents the leading cause
of blindness in the elderly. The macular retinal pigment epithelium (RPE) lies in a high …

Enriched environment and visual stimuli protect the retinal pigment epithelium and photoreceptors in a mouse model of non-exudative age-related macular …

HH Dieguez, JS Calanni, HE Romeo, A Alaimo… - Cell Death & …, 2021 - nature.com
Non-exudative age-related macular degeneration (NE-AMD), the main cause of blindness in
people above 50 years old, lacks effective treatments at the moment. We have developed a …

Mitochondrial quality control in non-exudative age-related macular degeneration: From molecular mechanisms to structural and functional recovery

HH Dieguez, HE Romeo, A Alaimo, NAB Aguirre… - Free Radical Biology …, 2024 - Elsevier
Non-exudative age-related macular degeneration (NE-AMD) is the leading blindness cause
in the elderly. Clinical and experimental evidence supports that early alterations in macular …

An ethologically relevant paradigm to assess defensive response to looming visual contrast stimuli

JS Calanni, ML Aranda, HH Dieguez, D Dorfman… - Scientific Reports, 2024 - nature.com
In the animal kingdom, threat information is perceived mainly through vision. The subcortical
visual pathway plays a critical role in the rapid processing of visual information-induced fear …

[HTML][HTML] Defective choroidal blood flow baroregulation and retinal dysfunction and pathology following sympathetic denervation of choroid

C Li, MEC Fitzgerald, N Del Mar… - … & visual science, 2018 - jov.arvojournals.org
Purpose: We sought to determine if sympathetic denervation of choroid impairs choroidal
blood flow (ChBF) regulation and harms retina. Methods: Rats received bilateral superior …

Vascular inflammation risk factors in retinal disease

I Soto, MP Krebs, AM Reagan… - Annual review of vision …, 2019 - annualreviews.org
Inflammation of the blood vessels that serve the central nervous system has been
increasingly identified as an early and possibly initiating event among neurodegenerative …

[HTML][HTML] Role of the superior salivatory nucleus in parasympathetic control of choroidal blood flow and in maintenance of retinal health

C Li, MEC Fitzgerald, N Del Mar, H Wang… - Experimental eye …, 2021 - Elsevier
The vasodilatory pterygopalatine ganglion (PPG) innervation of the choroid is under the
control of preganglionic input from the superior salivatory nucleus (SSN), the …