Computational approaches for prediction of pathogen-host protein-protein interactions

E Nourani, F Khunjush, S Durmuş - Frontiers in microbiology, 2015 - frontiersin.org
Infectious diseases are still among the major and prevalent health problems, mostly
because of the drug resistance of novel variants of pathogens. Molecular interactions …

Analysis of protein targets in pathogen–host interaction in infectious diseases: a case study on Plasmodium falciparum and Homo sapiens interaction network

S Saha, K Sengupta, P Chatterjee… - Briefings in …, 2018 - academic.oup.com
Infection and disease progression is the outcome of protein interactions between pathogen
and host. Pathogen, the role player of Infection, is becoming a severe threat to life as …

A new sequence based encoding for prediction of host–pathogen protein interactions

İ Kösesoy, M Gök, C Öz - Computational Biology and Chemistry, 2019 - Elsevier
Pathogen–host interactions are very important to figure out the infection process at the
molecular level, where pathogen proteins physically bind to human proteins to manipulate …

A weighted association rule mining method for predicting HCV-human protein interactions

M Indhumathy, AR Nabhan… - Current …, 2018 - ingentaconnect.com
Background: Hepatitis C Virus causes the most severe form of chronic liver disease and
nearly 200 million people worldwide are estimated to be infected with this virus. Much about …

Integrated statistical and rule-mining techniques for DNA methylation and gene expression data analysis

S Mallik, A Mukhopadhyay, U Maulik - Journal of Artificial Intelligence …, 2013 - sciendo.com
For determination of the relationships among significant gene markers, statistical analysis
and association rule mining are considered as very useful protocols. The first protocol …

Prediction of host-pathogen protein interactions by extended network model

İ Kösesoy, M Gök, T Kahveci - Turkish Journal of Biology, 2021 - journals.tubitak.gov.tr
Abstract Knowledge of the pathogen-host interactions between the species is essentialin
order to develop a solution strategy against infectious diseases. In vitro methods take …

Disease associated protein complex detection: a multi-objective evolutionary approach

S Ray, A Hossain, U Maulik - 2016 International conference on …, 2016 - ieeexplore.ieee.org
Biological networks such as protein-protein interaction networks (PPINs) play a crucial role
in cell biology of an organism and are widely studied in bioinformatics and biostatistics …

Computational Biology and Machine Learning Approaches to Study Mechanistic Microbiomehost Interactions

P Sudhakar, K Machiels, S Vermeire - 2020 - preprints.org
The microbiome, by virtue of its interactions with the host, is implicated in various host
functions including its influence on inflammation, nutrition, and homeostasis. Although …

A complete review of computational methods for human and HIV-1 protein interaction prediction

D Pal, KC Mondal - International Journal of Bioinformatics …, 2016 - inderscienceonline.com
Human Immunodeficiency Virus Type 1 (HIV-1) has grabbed the attention of virologists in
recent times owing to its life-threatening nature and epidemic spread throughout the globe …

Konak-patojen protein etkileşiminin hesaplamalı yöntemler ile tahmini

İ Kösesoy - 2018 - search.proquest.com
Türler arası patojen-konak protein etkileşimlerin bilinmesi enfeksiyonel hastalıkların teşhis
ve tedavisi için geliştirilecek çözüm stratejileri açısından hayati öneme sahiptir. Etkileşim …