Muscle fatigue is a common complaint in clinical practice. In humans, muscle fatigue can be
defined as exercise-induced decrease in the ability to produce force. Here, to provide a …

Glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital
for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose …

Since the introduction of the muscle biopsy technique in the late 1960s, our understanding
of the regulation of muscle glycogen storage and metabolism has advanced considerably …

Muscle glycogen is the main substrate during high-intensity exercise and large reductions
can occur after relatively short durations. Moreover, muscle glycogen is stored …

Studies performed at the beginning of the last century revealed the importance of
carbohydrate as a fuel during exercise, and the importance of muscle glycogen on …

Using a short-duration step protocol and continuous indirect calorimetry, whole-body rates of
fat and carbohydrate oxidation can be estimated across a range of exercise workloads …

Training with limited carbohydrate availability can stimulate adaptations in muscle cells to
facilitate energy production via fat oxidation. Here we investigated the effect of consistent …

l-Carnitine is an amino acid derivative widely known for its involvement in the transport of
long-chain fatty acids into the mitochondrial matrix, where fatty acid oxidation occurs …

The human body requires energy to function. Adenosine triphosphate (ATP) is the cellular
currency for energy-requiring processes including mechanical work (ie, exercise). ATP used …

The glycogen content of muscle determines not only our capacity for exercise but also the
signaling events that occur in response to exercise. The result of the shift in signaling is that …