Metalated heterocycles and their applications in synthetic organic chemistry

R Chinchilla, C Nájera, M Yus - Chemical reviews, 2004 - ACS Publications
The presence of heterocyclic moieties in all kinds of organic compounds of interest in
biology, pharmacology, optics, electronics, material sciences, and so on is sufficiently known …

Palladium Catalysts: Synthesis of Five-Membered N-Heterocycles Fused with Other Heterocycles

N Kaur - Catalysis Reviews, 2015 - Taylor & Francis
In recent decades, a large number of reports related to the synthesis of N, O, and S
containing heterocycles have appeared owing to a wide variety of their biological activity …

Palladium-catalyzed arylation and heteroarylation of indolizines

CH Park, V Ryabova, IV Seregin, AW Sromek… - Organic …, 2004 - ACS Publications
Palladium-Catalyzed Arylation and Heteroarylation of Indolizines | Organic Letters ACS ACS
Publications C&EN CAS Find my institution Log In Organic Letters ACS Publications. Most …

Synthesis of indolizine derivatives with selective antibacterial activity against Mycobacterium tuberculosis

LL Gundersen, C Charnock, AH Negussie… - European journal of …, 2007 - Elsevier
1-Substituted indolizines with activity against Mycobacterium tuberculosis have been
synthesized. The most active compounds carry an hydroxyphenylmethyl-or hydroxyalkyl …

Base-and ligand-free room-temperature synthesis of N-fused heteroaromatic compounds via the transition metal-catalyzed cycloisomerization protocol

IV Seregin, AW Schammel, V Gevorgyan - Organic letters, 2007 - ACS Publications
A new practical method for the synthesis of N-fused heterocycles via the transition metal-
catalyzed cycloisomerization of heterocyles possessing a propagyl group has been …

Domino Approach to Heterocycles-Based Unsymmetrical Triarylmethanes through Heteroannulation of 2-(2-Enynyl)-pyridines with Enaminones

F Ahmad, PK Ranga, S Fatma… - The Journal of Organic …, 2024 - ACS Publications
Herein, we report a copper-catalyzed protocol to access unsymmetrical triarylmethanes
containing both indolizine and the chromone scaffolds in the same molecule via a 5-endo …

15-Lipoxygenase inhibitors: a patent review

H Sadeghian, A Jabbari - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
Introduction: 15-Lipoxygenases (15-LOXes) are a family of iron-containing proteins that
have the capability for unsaturated fatty acid peroxidation in animals and plants. Two types …

Investigation of antifungal properties of synthetic dimethyl-4-bromo-1-(substituted benzoyl) pyrrolo [1, 2-a] quinoline-2, 3-dicarboxylates analogues: Molecular docking …

V Uppar, S Chandrashekharappa, C Shivamallu, SP… - Molecules, 2021 - mdpi.com
Candida albicans, an opportunistic fungal pathogen, frequently colonizes immune-
compromised patients and causes mild to severe systemic reactions. Only few antifungal …

[HTML][HTML] Pd-catalyzed asymmetric oxidative CH/CH cross-coupling reaction between dialkylaminomethylferrocenes and indolizines

CX Liu, WW Zhang, P Yang, F Zhao, Z Feng, Q Wang… - Chem Catalysis, 2022 - cell.com
Oxidative CH/CH cross-coupling reactions between two (hetero) arenes through 2-fold CH
activation offer rapid assembly of diverse bi (hetero) aryls. Herein, a Pd-catalyzed …

Indolizine synthesis via oxidative cross-coupling/cyclization of alkenes and 2-(pyridin-2-yl) acetate derivatives

RR Liu, JJ Hong, CJ Lu, M Xu, JR Gao, YX Jia - Organic letters, 2015 - ACS Publications
A novel copper/I2-mediated oxidative cross-coupling/cyclization of 2-(pyridin-2-yl) acetate
derivatives and simple olefins is developed, which provides a straightforward and efficient …