Canine lymphoma, more than a morphological diagnosis: what we have learned about diffuse large B-cell lymphoma
L Aresu - Frontiers in Veterinary Science, 2016 - frontiersin.org
Diffuse large B-cell lymphoma (DLBCL) is the most common canine aggressive B-cell
lymphoma worldwide, and new recent molecular approaches have shown that DLBCL …
lymphoma worldwide, and new recent molecular approaches have shown that DLBCL …
Impact of interleukin-6 on drug-metabolizing enzymes and transporters in intestinal cells
F Simon, J Garcia, L Guyot, J Guitton, G Vilchez… - The AAPS journal, 2020 - Springer
Inflammatory response is characterized by an increase of several cytokines. Some are
known to modify drugs pharmacokinetic by reducing the expression levels of drug …
known to modify drugs pharmacokinetic by reducing the expression levels of drug …
Comparative aspects of molecular mechanisms of drug resistance through ABC transporters and other related molecules in canine lymphoma
H Tomiyasu, H Tsujimoto - Veterinary sciences, 2015 - mdpi.com
The most important causes of treatment failure in canine lymphoma include intrinsic or
acquired drug resistance. Thus, elucidation of molecular mechanisms of drug resistance is …
acquired drug resistance. Thus, elucidation of molecular mechanisms of drug resistance is …
Expression and activity of multidrug resistance proteins in mature endothelial cells and their precursors: A challenging correlation
A Krawczenko, A Bielawska-Pohl, K Wojtowicz… - PLoS …, 2017 - journals.plos.org
Active cellular transporters of harmful agents—multidrug resistance (mdr) proteins—are
present in tumor, stem and endothelial cells, among others. While mdr proteins are broadly …
present in tumor, stem and endothelial cells, among others. While mdr proteins are broadly …
Comparison of chemotherapy outcomes between normal and high serum cortisol concentration in dogs with lymphoma
H Yamazaki, K Bunbai, T Deguchi… - Journal of Veterinary …, 2024 - Wiley Online Library
Background Increased serum cortisol (COR) concentrations may induce glucocorticoid
resistance by down‐regulation of glucocorticoid receptor (GCR), resulting in decreased …
resistance by down‐regulation of glucocorticoid receptor (GCR), resulting in decreased …
Impact of interleukin‐6 on drug transporters and permeability in the hCMEC/D3 blood–brain barrier model
F Simon, L Guyot, J Garcia, G Vilchez… - Fundamental & …, 2021 - Wiley Online Library
The blood–brain barrier (BBB) is a highly selective membrane composed predominantly of
brain capillary endothelial cells expressing drug efflux transporters that prevent substrates …
brain capillary endothelial cells expressing drug efflux transporters that prevent substrates …
P-glycoprotein activity at diagnosis does not predict therapy outcome and survival in canine B-cell lymphoma
Simple Summary Clinical experience in human and canine clinics shows that following
initial response to treatment, drug-resistant cancer cells frequently evolve and eventually …
initial response to treatment, drug-resistant cancer cells frequently evolve and eventually …
Evaluation of Novel Diaza Cage Compounds as MRP Modulators in Cancer Cells
H Döring, D Kreutzer, J von Veh… - Anti-Cancer Agents …, 2025 - benthamdirect.com
Aim Novel MRP modulators are needed to combat MRP-mediated multidrug resistance
(MDR) in cancer cells. Background Anticancer drug resistance is the main problem in cancer …
(MDR) in cancer cells. Background Anticancer drug resistance is the main problem in cancer …
自噬在视网膜母细胞瘤Y79 细胞顺铂耐药中的作用及其机制
刘颖， 苏杰， 王林洪 - 肿瘤防治研究, 2018 - zlfzyj.com
SNAI2基因对低转移潜能乳腺癌细胞恶性特征的影响及机制周园红, 罗幼珍, 刘强, 刘晓雯引用本文:
Page 1 SNAI2基因对低转移潜能乳腺癌细胞恶性特征的影响及机制 周园红, 罗幼珍, 刘强, 刘晓雯 …
Page 1 SNAI2基因对低转移潜能乳腺癌细胞恶性特征的影响及机制 周园红, 罗幼珍, 刘强, 刘晓雯 …
[HTML][HTML] 低频超声联合微泡造影剂通过激活内质网应激逆转前列腺癌紫杉醇耐药
武雨琦， 王祥卫 - 2018 - aammt.tmmu.edu.cn
目的探讨低频超声联合微泡造影剂辅助紫杉醇逆转前列腺癌耐药的作用和机制.
方法筛选超声辐照紫杉醇耐药前列腺癌细胞株PC-3R 的非毒性照射时间; 将PC-3R …
方法筛选超声辐照紫杉醇耐药前列腺癌细胞株PC-3R 的非毒性照射时间; 将PC-3R …