Regulatory (Treg) cells are key regulators of inflammation and important for immune
tolerance and homeostasis. A major progress has been made in the identification and …

Ankylosing spondylitis is a complicated consequence of genetic predisposition and
environmental factors. Enthesitis is believed to be the hallmark of ankylosing spondylitis …

Ankylosing spondylitis is a chronic, progressive disease, and its treatment is relevant to the
gut microbiota. Anti‐tumor necrosis factor‐alpha (anti‐TNF‐α) therapy alters the gut …

Known as a pivotal immunohemostatic response, immunothrombosis is activated to restrict
the diffusion of pathogens. This beneficial intravascular defensive mechanism represents …

Objective. Accumulating evidence indicates that regulatory T cells (Tregs) may be involved
in the pathogenesis of ankylosing spondylitis (AS). As different markers have been used to …

Abstract Context: miR-146a, its targets (IRAK1, TRAF6) and NF-κB transcription factor play a
fundamental role in rheumatoid arthritis (RA). Positive effects of drug β-d-mannuronic acid …

Alginate oligosaccharides (AOS) can be obtained by acidolysis and enzymatic hydrolysis.
The products obtained by different methods have different structures and physiological …

Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease involving the axial
skeleton, peripheral joints, and extra-articular manifestations like psoriasis, inflammatory …

Studies on the number and proportion of regulatory T cells (Tregs) in ankylosing spondylitis
(AS) patients have been controversial, which has led to a disagreement regarding the role of …

Background The oral administration of drug β-d-mannuronic acid (M2000) showed a potent
therapeutic effect in phase I/II study in rheumatoid arthritis (RA) patients. Here, our aim is to …