Interaction of cardiovascular nonmodifiable risk factors, comorbidities and comedications with ischemia/reperfusion injury and cardioprotection by pharmacological …

P Ferdinandy, I Andreadou, GF Baxter, HE Bøtker… - Pharmacological …, 2023 - Elsevier
Preconditioning, postconditioning, and remote conditioning of the myocardium enhance the
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …

Preclinical multi-target strategies for myocardial ischemia-reperfusion injury

Y Li, Y Gao, G Li - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Despite promising breakthroughs in diagnosing and treating acute coronary syndromes,
cardiovascular disease's high global mortality rate remains indisputable. Nearly half of these …

[HTML][HTML] Crosstalk among Reactive Oxygen Species, Autophagy and Metabolism in Myocardial Ischemia and Reperfusion Stages

Y Peng, Y Tao, L Liu, J Zhang, B Wei - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Myocardial ischemia is the most common cardiovascular disease. Reperfusion, an important
myocardial ischemia tool, causes unexpected and irreversible damage to cardiomyocytes …

[HTML][HTML] Early Cardiac Ischemia–reperfusion injury: interactions of autophagy with Galectin-3 and oxidative stress

S Al-Salam, S Hashmi, GS Jagadeesh, M Sudhadevi… - Biomedicines, 2024 - mdpi.com
Background: Cardiovascular diseases are the leading cause of death worldwide, including
the United Arab Emirates. Ischemia–reperfusion (IR) injury results in the death of cardiac …

Protective and deleterious effects of autophagy in the setting of myocardial ischemia/reperfusion injury: an overview

B Mokhtari, R Badalzadeh - Molecular Biology Reports, 2022 - Springer
Introduction: Autophagy is known as a conserved mechanism in order to preserve cell
survival under various stress conditions via maintaining cellular homeostasis. Although …

Alpha-lipoic acid enhances ischemic postconditioning-mediated improvement of myocardial infarction and apoptosis in diabetic rats with ischemia/reperfusion injury

S Gholami, R Badalzadeh… - Canadian Journal of …, 2023 - cdnsciencepub.com
This work evaluated the combined effects of alpha-lipoic acid (ALA) and ischemic
postconditioning (Post) on myocardial infarction and cell death in rats with chronic type-II …

The effects of lipoic acid on respiratory diseases

X Guo, S Wu, J Shang, W Dong, Y Li, Q Peng… - International …, 2023 - Elsevier
Respiratory diseases, including lung cancer, pulmonary fibrosis, asthma, and the recently
emerging fatal coronavirus disease-19 (COVID-19), are the leading causes of illness and …

The additive effects of nicotinamide mononucleotide and melatonin on mitochondrial biogenesis and fission/fusion, autophagy, and microRNA-499 in the aged rat …

B Mokhtari, L Hosseini, PF Høilund-Carlsen… - Naunyn-Schmiedeberg's …, 2023 - Springer
The prognosis of myocardial ischemia/reperfusion (I/R) injury is poor in elderly patients.
Aging increases the susceptibility of the heart to cell death from I/R injury and prevents the …

Alpha-lipoic acid potentiates the anti-arrhythmic effects of ischemic postconditioning in the setting of cardiac ischemia/reperfusion injury in diabetic rats

S Gholami, B Mokhtari, R Badalzadeh - Journal of Diabetes & Metabolic …, 2022 - Springer
Background Prevention of lethal ventricular arrhythmias induced by myocardial
ischemia/reperfusion (I/R) in diabetic patients is the major goal of cardioprotective strategies …

Amplification of Cardioprotective Response of Remote Ischemic Preconditioning in Rats by Quercetin: Potential Role of Activation of mTOR-dependent Autophagy and …

A Kandpal, K Kumar, S Singh, HN Yadav… - … Drugs and Therapy, 2024 - Springer
Objectives Noninvasive remote ischemic preconditioning (RIPC) is a practical, acceptable,
and feasible conditioning technique reported to provide cardioprotection in myocardial …