The gut microbiota–brain axis in behaviour and brain disorders

LH Morais, HL Schreiber IV… - Nature Reviews …, 2021 - nature.com
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …

[HTML][HTML] The vagus nerve at the interface of the microbiota-gut-brain axis

B Bonaz, T Bazin, S Pellissier - Frontiers in neuroscience, 2018 - frontiersin.org
The microbiota, the gut, and the brain communicate through the microbiota-gut-brain axis in
a bidirectional way that involves the autonomic nervous system. The vagus nerve (VN), the …

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

GB Rogers, DJ Keating, RL Young, ML Wong… - Molecular …, 2016 - nature.com
The human body hosts an enormous abundance and diversity of microbes, which perform a
range of essential and beneficial functions. Our appreciation of the importance of these …

[HTML][HTML] Altered fecal microbiota composition in patients with major depressive disorder

H Jiang, Z Ling, Y Zhang, H Mao, Z Ma, Y Yin… - Brain, behavior, and …, 2015 - Elsevier
Studies using animal models have shown that depression affects the stability of the
microbiota, but the actual structure and composition in patients with major depressive …

Dysbiosis of the gut microbiota in disease

S Carding, K Verbeke, DT Vipond… - Microbial ecology in …, 2015 - Taylor & Francis
There is growing evidence that dysbiosis of the gut microbiota is associated with the
pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include …

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

SM O'Mahony, G Clarke, YE Borre, TG Dinan… - Behavioural brain …, 2015 - Elsevier
The brain-gut axis is a bidirectional communication system between the central nervous
system and the gastrointestinal tract. Serotonin functions as a key neurotransmitter at both …

The role of gut dysbiosis in the pathophysiology of neuropsychiatric disorders

N Anand, VR Gorantla, SB Chidambaram - Cells, 2022 - mdpi.com
Mounting evidence shows that the complex gut microbial ecosystem in the human
gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via …

Growing up in a bubble: using germ-free animals to assess the influence of the gut microbiota on brain and behavior

P Luczynski, KA McVey Neufeld… - International Journal …, 2016 - academic.oup.com
There is a growing recognition of the importance of the commensal intestinal microbiota in
the development and later function of the central nervous system. Research using germ-free …

A meta-analysis of the use of probiotics to alleviate depressive symptoms

QX Ng, C Peters, CYX Ho, DY Lim, WS Yeo - Journal of affective disorders, 2018 - Elsevier
Introduction Some preclinical and clinical studies have demonstrated the positive impact of
probiotic supplementation on depressive symptoms. This paper aims to provide an updated …

Microbes and mental health: A review

R Rieder, PJ Wisniewski, BL Alderman… - Brain, behavior, and …, 2017 - Elsevier
There is a growing emphasis on the relationship between the microorganisms inhabiting the
gut (gastrointestinal microbiota) and human health. The emergence of a microbiota-gut …