Peptide-drug conjugates and their targets in advanced cancer therapies

P Hoppenz, S Els-Heindl, AG Beck-Sickinger - Frontiers in chemistry, 2020 - frontiersin.org
Cancer became recently the leading cause of death in industrialized countries. Even though
standard treatments achieve significant effects in growth inhibition and tumor elimination …

Next generation of boron neutron capture therapy (BNCT) agents for cancer treatment

P Coghi, J Li, NS Hosmane… - Medicinal Research …, 2023 - Wiley Online Library
Boron neutron capture therapy (BNCT) is one of the most promising treatments among
neutron capture therapies due to its long‐term clinical application and unequivocally …

Progress in three-dimensional aromatic-like closo-dodecaborate

X Zhao, Z Yang, H Chen, Z Wang, X Zhou… - Coordination Chemistry …, 2021 - Elsevier
The continuous discovery and derivatization of members of the closed borane family
indicate that boron chemistry is about to embark on a development trajectory similar to that …

The dawn of a new era: tumor-targeting boron agents for neutron capture therapy

T Luo, W Huang, F Chu, T Zhu, B Feng… - Molecular …, 2023 - ACS Publications
Cancer is widely recognized as one of the most devastating diseases, necessitating the
development of intelligent diagnostic techniques, targeted treatments, and early prognosis …

Multi-functional boron-delivery agents for boron neutron capture therapy of cancers

SO Oloo, KM Smith, MGH Vicente - Cancers, 2023 - mdpi.com
Simple Summary Many boron-containing compounds have been synthesized and proposed
as boron-delivery agents for boron neutron capture therapy for cancers, including brain …

Multifunctional high boron content MOFs nano-co-crystals for precise boron neutron capture therapy for brain glioma in situ

Z Wang, Z Chen, Z Zhang, J Li, K Chen, H Liang, L Lv… - Nano Today, 2022 - Elsevier
Multifunctional high boron content MOFs nano-co-crystals were assembled and architected
for precise boron neutron capture therapy (BNCT) of brain glioma. Zirconium and mesotetra …

Dodecaborate-encapsulated extracellular vesicles with modification of cell-penetrating peptides for enhancing macropinocytotic cellular uptake and biological activity …

S Hirase, A Aoki, Y Hattori, K Morimoto… - Molecular …, 2022 - ACS Publications
Boron neutron capture therapy (BNCT) is a radiation therapy for cancer. In BNCT, the
internalization of boron-10 atoms by cancer cells induces cell death through the generation …

Peptide Conjugated Boron Neutron Capture Therapy for Enhanced Tumor Targeting

VGSS Jyothi, N Kommineni - Nanotheranostics, 2024 - pmc.ncbi.nlm.nih.gov
A cutting-edge non-invasive cancer treatment method called boron neutron capture therapy
(BNCT) allows for the removal of cancerous tumor cells with the least possible damage to …

Theranostics in boron neutron capture therapy

WAG Sauerwein, L Sancey, E Hey-Hawkins, M Kellert… - Life, 2021 - mdpi.com
Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells
without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method …

Proposal of recommended experimental protocols for in vitro and in vivo evaluation methods of boron agents for neutron capture therapy

Y Hattori, T Andoh, S Kawabata, N Hu… - Journal of radiation …, 2023 - academic.oup.com
Recently, boron neutron capture therapy (BNCT) has been attracting attention as a
minimally invasive cancer treatment. In 2020, the accelerator-based BNCT with L-BPA …