Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy
Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …
cancer therapy due to their ability to overcome many of the key challenges currently being …
Advanced engineered nanoparticulate platforms to address key biological barriers for delivering chemotherapeutic agents to target sites
The widespread development of nanocarriers to deliver chemotherapeutics to specific tumor
sites has been motivated by the lack of selective targeting during chemotherapy inducing …
sites has been motivated by the lack of selective targeting during chemotherapy inducing …
Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap
Although great success has been obtained in the clinic, the current immune checkpoint
inhibitors still face two challenging problems: low response rate and immune-related …
inhibitors still face two challenging problems: low response rate and immune-related …
Nanoengineered immune niches for reprogramming the immunosuppressive tumor microenvironment and enhancing cancer immunotherapy
H Phuengkham, L Ren, IW Shin, YT Lim - Advanced Materials, 2019 - Wiley Online Library
Cancer immunotherapies that harness the body's immune system to combat tumors have
received extensive attention and become mainstream strategies for treating cancer. Despite …
received extensive attention and become mainstream strategies for treating cancer. Despite …
[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
Nano codelivery of oxaliplatin and folinic acid achieves synergistic chemo-immunotherapy with 5-fluorouracil for colorectal cancer and liver metastasis
FOLFOX, the combinational strategy of folinic acid (FnA), 5-fluorouracil (5-Fu), and
oxaliplatin (OxP), has been used as standard treatment of colorectal cancer (CRC) for …
oxaliplatin (OxP), has been used as standard treatment of colorectal cancer (CRC) for …
Nanomaterials for cancer immunotherapy
Cancer immunotherapy is quickly growing to be the fourth most important cancer therapy,
after surgery, radiation therapy, and chemotherapy. Immunotherapy is the most promising …
after surgery, radiation therapy, and chemotherapy. Immunotherapy is the most promising …
Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy
Abstract Anti-programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1)
antibodies are currently used in the clinic to interupt the PD-1/PD-L1 immune checkpoint …
antibodies are currently used in the clinic to interupt the PD-1/PD-L1 immune checkpoint …
Nanoparticle-mediated remodeling of the tumor microenvironment to enhance immunotherapy
Nanoscience has long been lauded as a method through which tumor-associated barriers
could be overcome. As successful as cancer immunotherapy has been, limitations …
could be overcome. As successful as cancer immunotherapy has been, limitations …
Materials for immunotherapy
Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …
preclinical studies. The interplay of chemistry and materials has resulted in improved …