Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice

Z Xiao, J He, G Su, M Chen, Y Hou, S Chen… - Arthritis Research & …, 2018 - Springer
Background Studies on the relationship between osteoporosis and intervertebral disc
degeneration (IVDD) are inconsistent. Therefore, we assessed whether IVDD is affected by …

The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model

Y Luo, L Zhang, WY Wang, QF Hu, HP Song… - European Spine …, 2015 - Springer
Purpose Intervertebral disc degeneration related to postmenopausal osteoporosis is an
important issue in spinal disorder research. This study aimed to investigate the effects of …

[HTML][HTML] Conventional finite element models estimate the strength of metastatic human vertebrae despite alterations of the bone's tissue and structure

MA Stadelmann, DE Schenk, G Maquer, C Lenherr… - Bone, 2020 - Elsevier
Introduction Pathologic vertebral fractures are a major clinical concern in the management of
cancer patients with metastatic spine disease. These fractures are a direct consequence of …

Comparison of patient-specific computational models vs. clinical follow-up, for adjacent segment disc degeneration and bone remodelling after spinal fusion

M Rijsbergen, B van Rietbergen, V Barthelemy… - PLoS …, 2018 - journals.plos.org
Spinal fusion is a standard surgical treatment for patients suffering from low back pain
attributed to disc degeneration. However, results are somewhat variable and unpredictable …

TELD with limited foraminoplasty has potential biomechanical advantages over TELD with large annuloplasty: an in-silico study

J Li, C Xu, X Zhang, Z Xi, M Liu, Z Fang, N Wang… - BMC musculoskeletal …, 2021 - Springer
Background Facetectomy, an important procedure in the in–out and out–in techniques of
transforaminal endoscopic lumbar discectomy (TELD), is related to the deterioration of the …

Correspondence between bone mineral density and intervertebral disc degeneration across age and sex

J Kaiser, B Allaire, PM Fein, D Lu, M Jarraya… - Archives of …, 2018 - Springer
The distribution of bone tissue within the vertebra can modulate vertebral strength
independently of average density and may change with age and disc degeneration. Our …

Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats

Y Luo, L Zhang, WY Wang, QF Hu, HP Song, YL Su… - Bone, 2013 - Elsevier
OBJECTIVE: Increasing evidence has revealed a positive correlation between
postmenopausal osteoporosis and intervertebral disc degeneration, the underlying …

In vivo correlates between daily physical activity and intervertebral disc health

JA Bowden, AE Bowden, H Wang… - Journal of …, 2018 - Wiley Online Library
Physical activity impacts health and disease in multiple body tissues including the
intervertebral discs. Fluid flow within the disc is an indicator of disc health that can be …

The association of lumbar disc herniation with lumbar volumetric bone mineral density in a cross-sectional Chinese study

J Geng, L Wang, Q Li, P Huang, Y Liu, GM Blake… - Diagnostics, 2021 - mdpi.com
Little is known about the effect of lumbar intervertebral disc herniation (LDH) on lumbar bone
mineral density (BMD), and few previous studies have used quantitative computed …

Association between bone mineral density and lumbar disc degeneration

S Salo, V Leinonen, T Rikkonen, P Vainio, J Marttila… - Maturitas, 2014 - Elsevier
Objectives Higher vertebral bone mineral density (BMD) has been found to be related with
lumbar disc degeneration (LDD), while relationship between femoral neck BMD and LDD …