Depressive and biopsychosocial frailty phenotypes: impact on late-life cognitive disorders
In older age, frailty is a detrimental transitional status of the aging process featuring an
increased susceptibility to stressors defined by a clinical reduction of homoeostatic reserves …
increased susceptibility to stressors defined by a clinical reduction of homoeostatic reserves …
[HTML][HTML] Shared and Distinct White Matter Alterations in Major Depression and Bipolar Disorder: A Systematic Review and Meta-Analysis
Y Xu, X Cheng, Y Li, H Shen, Y Wan, L Ping… - Journal of Integrative …, 2024 - imrpress.com
Background: Identifying white matter (WM) microstructural similarities and differences
between major depressive disorder (MDD) and bipolar disorder (BD) is an important way to …
between major depressive disorder (MDD) and bipolar disorder (BD) is an important way to …
Exploring the shared genetic basis of major depressive disorder and frailty
W Fu, R Xu, P Bian, X Li, K Yang, X Wang - Journal of Affective Disorders, 2024 - Elsevier
Background Major depressive disorder (MDD) and frailty impose substantial health and
economic burdens. MDD is recognized as a significant risk factor for frailty, but the genetic …
economic burdens. MDD is recognized as a significant risk factor for frailty, but the genetic …
Lateralized White Matter Integrity Changes Across the Lifespan in Major Depression: AES-SDM Meta-analysis
E Zhang, AO Hauson, AA Pollard, D Zelman… - Psychiatry Research …, 2025 - Elsevier
This meta-analysis examined white matter fractional anisotropy (FA) differences across the
lifespan to better understand underlying neurobiological mechanisms of major depressive …
lifespan to better understand underlying neurobiological mechanisms of major depressive …
Coexisting depression and frailty as an accelerated aging phenotype of late-life depression: Commentary on “Neuroimaging features of depression-frail phenotype in …
WD Taylor - International Psychogeriatrics, 2023 - cambridge.org
Conceptualizing late-life depression (LLD) in context of aging provides insights into how the
underlying neurobiology of LLD contributes to adverse clinical outcomes. It may be …
underlying neurobiology of LLD contributes to adverse clinical outcomes. It may be …