In vivo range verification in particle therapy

K Parodi, JC Polf - Medical physics, 2018 - Wiley Online Library
Exploitation of the full potential offered by ion beams in clinical practice is still hampered by
several sources of treatment uncertainties, particularly related to the limitations of our ability …

Review of medical radiography and tomography with proton beams

RP Johnson - Reports on progress in physics, 2017 - iopscience.iop.org
The use of hadron beams, especially proton beams, in cancer radiotherapy has expanded
rapidly in the past two decades. To fully realize the advantages of hadron therapy over …

Proton radiography and tomography with application to proton therapy

G Poludniowski, NM Allinson… - The British journal of …, 2015 - academic.oup.com
Proton radiography and tomography have long promised benefit for proton therapy. Their
first suggestion was in the early 1960s and the first published proton radiographs and CT …

Latest developments in in-vivo imaging for proton therapy

K Parodi - The British journal of radiology, 2020 - academic.oup.com
Owing to the favorable physical and biological properties of swift ions in matter, their
application to radiation therapy for highly selective cancer treatment is rapidly spreading …

Patient-specific stopping power calibration for proton therapy planning based on single-detector proton radiography

PJ Doolan, M Testa, G Sharp… - Physics in Medicine …, 2015 - iopscience.iop.org
A simple robust optimizer has been developed that can produce patient-specific calibration
curves to convert x-ray computed tomography (CT) numbers to relative stopping powers (HU …

Towards achieving the full clinical potential of proton therapy by inclusion of LET and RBE models

B Jones - Cancers, 2015 - mdpi.com
Despite increasing use of proton therapy (PBT), several systematic literature reviews show
limited gains in clinical outcomes, with publications mostly devoted to recent technical …

Proton tracking in a high-granularity Digital Tracking Calorimeter for proton CT purposes

HES Pettersen, J Alme, A Biegun… - Nuclear Instruments and …, 2017 - Elsevier
Radiation therapy with protons as of today utilizes information from x-ray CT in order to
estimate the proton stopping power of the traversed tissue in a patient. The conversion from …

Proof of principle of helium‐beam radiography using silicon pixel detectors for energy deposition measurement, identification, and tracking of single ions

T Gehrke, R Gallas, O Jäkel, M Martišíková - Medical physics, 2018 - Wiley Online Library
Purpose Hadron therapy has the capability to provide a high dose conformation to tumor
regions. However, it requires an accurate target positioning. Thus, the precise monitoring of …

Theoretical and experimental comparison of proton and helium-beam radiography using silicon pixel detectors

T Gehrke, C Amato, S Berke… - Physics in Medicine & …, 2018 - iopscience.iop.org
Ion-beam radiography (iR ad) could potentially improve the quality control of ion-beam
therapy. The main advantage of iR ad is the possibility to directly measure the integrated …

Proton computed tomography reconstruction using a backprojection-then-filtering approach

G Poludniowski, NM Allinson… - Physics in Medicine & …, 2014 - iopscience.iop.org
A novel approach to proton CT reconstruction using backprojection-then-filtering (BPF) is
proposed. A list-mode algorithm is formulated accommodating non-linear proton paths. The …