Recovery from stroke: current concepts and future perspectives

C Grefkes, GR Fink - Neurological research and practice, 2020 - Springer
Stroke is a leading cause of acquired, permanent disability worldwide. Although the
treatment of acute stroke has been improved considerably, the majority of patients to date …

Diaschisis: past, present, future

E Carrera, G Tononi - Brain, 2014 - academic.oup.com
After a century of false hopes, recent studies have placed the concept of diaschisis at the
centre of the understanding of brain function. Originally, the term 'diaschisis' was coined by …

Connectivity-based approaches in stroke and recovery of function

C Grefkes, GR Fink - The Lancet Neurology, 2014 - thelancet.com
After focal damage, cerebral networks reorganise their structural and functional anatomy to
compensate for both the lesion itself and remote effects. Novel developments in the analysis …

Neuroimaging of stroke recovery from aphasia–Insights into plasticity of the human language network

G Hartwigsen, D Saur - Neuroimage, 2019 - Elsevier
The role of left and right hemisphere brain regions in language recovery after stroke-induced
aphasia remains controversial. Here, we summarize how neuroimaging studies increase the …

Reorganization of cerebral networks after stroke: new insights from neuroimaging with connectivity approaches

C Grefkes, GR Fink - Brain, 2011 - academic.oup.com
The motor system comprises a network of cortical and subcortical areas interacting via
excitatory and inhibitory circuits, thereby governing motor behaviour. The balance within the …

Cortical reorganization after stroke: how much and how functional?

C Grefkes, NS Ward - The Neuroscientist, 2014 - journals.sagepub.com
The brain has an intrinsic capacity to compensate for structural damage through
reorganizing of surviving networks. These processes are fundamental for recovery of …

Activation likelihood estimation meta-analysis of motor-related neural activity after stroke

AK Rehme, SB Eickhoff, C Rottschy, GR Fink… - Neuroimage, 2012 - Elsevier
Over the past two decades, several functional neuroimaging experiments demonstrated
changes in neural activity in stroke patients with motor deficits. Conclusions from single …

Mapping human brain lesions and their functional consequences

HO Karnath, C Sperber, C Rorden - Neuroimage, 2018 - Elsevier
Neuroscience has a long history of inferring brain function by examining the relationship
between brain injury and subsequent behavioral impairments. The primary advantage of this …

Dynamic causal modeling of cortical activity from the acute to the chronic stage after stroke

AK Rehme, SB Eickhoff, LE Wang, GR Fink, C Grefkes - Neuroimage, 2011 - Elsevier
Functional neuroimaging studies frequently demonstrated that stroke patients show bilateral
activity in motor and premotor areas during movements of the paretic hand in contrast to a …

Cerebral network disorders after stroke: Evidence from imaging‐based connectivity analyses of active and resting brain states in humans

AK Rehme, C Grefkes - The Journal of physiology, 2013 - Wiley Online Library
Stroke causes a sudden disruption of physiological brain function which leads to
impairments of functional brain networks involved in voluntary movements. In some cases …