The beneficial actions of nonsteroidal anti‐inflammatory drugs (NSAIDs) have been linked to
their ability to inhibit inducible COX‐2 at sites of inflammation, and their side effects (eg …

Background & Aims: Data indicate that cyclooxygenase-2–specific inhibitors cause less
gastroduodenal mucosal damage than nonspecific NSAIDS, but their effects on the small …

Four types of experimental chronic ulcer models, named acetic acid ulcer models, have
been developed to examine the healing process of peptic ulcers, screen anti-ulcer drugs …

Skeletal muscle regeneration comprises several overlapping cellular processes, including
inflammation and myogenesis. Prostaglandins (PGs) may regulate muscle regeneration …

Hepatocyte growth factor plays multiple roles in cancer, by acting as a motility and invasion
stimulating factor, promoting metastasis and tumour growth. Furthermore, it acts as a …

The aggressive biology of human pancreatic adenocarcinoma has been linked with
overexpression of vascular endothelial growth factor (VEGF). Constitutive activation of the …

Purpose: Helicobacter pylori causes gastric damage and is involved in gastric
carcinogenesis. Vascular endothelial growth factor (VEGF) plays a major role in gastric …

The cyclooxygenase-2 (COX-2) enzyme has a fundamental role in the carcinogenesis of
colorectal cancer. The anticarcinogenic mechanisms of NSAIDs are not completely …

Background There have been cases reporting anaplastic lymphoma kinase (ALK) tyrosine
kinase inhibitors (TKIs) and associated serious gastrointestinal (GI) adverse drug reactions …

The hepatocyte growth factor (HGF) receptor, Met, has established oncogenic properties;
however, its expression and function in esophageal adenocarcinoma (EA) remain poorly …