Nucleation of new peptide and protein aggregates on the surfaces of amyloid fibrils of the
same peptide or protein has emerged in the past two decades as a major pathway for both …

Crystallization is an effective, low-cost purification & formulation process widely applied to
pharmaceuticals and fine chemicals. This review describes recent advances in research on …

This scientific paper presents an overview of continuous solution crystallization in the
pharmaceutical industry. Since the specific knowledge spectrum of precipitation is very …

Co-precipitation is by far the most common synthesis for magnetic iron oxide nanoparticles
(IONPs), as cheap and environmentally friendly precursors and simple experimental …

Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …

Inhibition of amyloid β peptide (Aβ) aggregation is an important goal due to the connection
of this process with Alzheimer's disease. Traditionally, inhibitors were developed with an aim …

The challenges and opportunities of developing API manufacturing processes continue to
grow. Molecular complexity of APIs is increasing, process development times are …

Continuous crystallization has been proposed as the downstream processing step for the
purification of pharmaceutical proteins aimed at alleviating the manufacturing bottleneck …

Generation of bubbles in a T-junction microdevice is vital to microfluidic applications for its
advantages of easy fabrication and scaling-up, but the bubble generation in liquids with a …

The performances of slug flow gas–liquid reactors are mostly determined by slug length,
especially for the high gas–liquid flow rate ratio condition. This work is the first time to report …