[HTML][HTML] Ovariectomized rat model of osteoporosis: a practical guide

N Yousefzadeh, K Kashfi, S Jeddi, A Ghasemi - EXCLI journal, 2020 - ncbi.nlm.nih.gov
Osteoporosis affects about 200 million people worldwide and is a silent disease until a
fracture occurs. Management of osteoporosis is still a challenge that warrants further studies …

[HTML][HTML] Estrogenic flavonoids and their molecular mechanisms of action

R Kiyama - The Journal of Nutritional Biochemistry, 2023 - Elsevier
Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

Sarcopenic obesity: involvement of oxidative stress and beneficial role of antioxidant flavonoids

UJ Jung - Antioxidants, 2023 - mdpi.com
Sarcopenic obesity, which refers to concurrent sarcopenia and obesity, is characterized by
decreased muscle mass, strength, and performance along with abnormally excessive fat …

Age-related changes in skeletal muscle iron homeostasis

FM Alves, S Ayton, AI Bush, GS Lynch… - The Journals of …, 2023 - academic.oup.com
Sarcopenia is an age-related condition of slow, progressive loss of muscle mass and
strength, which contributes to frailty, increased risk of hospitalization and mortality, and …

Moderating AKT signaling with baicalein protects against weight loss by preventing muscle atrophy in a cachexia model caused by CT26 colon cancer

G Song, WY Park, W Jiao, JY Park, SJ Jung… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Cancer cachexia is a type of energy-wasting syndrome characterized by fatigue, anorexia,
muscle weakness, fat loss, and systemic inflammation. Baicalein, a flavonoid with bioactive …

Inhibiting 5‐lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signalling and insulin‐like growth factor‐1

HJ Kim, SW Kim, SH Lee, DW Jung… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Skeletal muscle atrophy can occur in response to numerous factors, such as
ageing and certain medications, and produces a major socio‐economic burden. At present …

Effects of the traditional Chinese medicine baicalein on the viability of random pattern skin flaps in rats

R Lin, J Lin, S Li, J Ding, H Wu, G Xiang… - Drug Design …, 2018 - Taylor & Francis
Background Random skin flaps are routinely placed during plastic and reconstructive
surgery, but the distal areas often develop ischemia and necrosis. Baicalein, a major …

[HTML][HTML] Promotion of healthy aging through the nexus of gut microbiota and dietary phytochemicals

LM Beaver, PE Jamieson, CP Wong, M Hosseinikia… - Advances in …, 2025 - Elsevier
Aging is associated with the decline of tissue and cellular functions, which can promote the
development of age-related diseases like cancer, cardiovascular disease …

Natural inhibitors against potential targets of cyclooxygenase, lipoxygenase and leukotrienes

R Dey, S Dey, A Samadder… - … Chemistry & High …, 2022 - ingentaconnect.com
Background: Cyclooxygenase (COX) and Lipoxygenase (LOX) enzymes catalyze the
production of pain mediators like Prostaglandins (PGs) and Leukotrienes (LTs), respectively …

Myotendinous junction plasticity in aged ovariectomized rats submitted to aquatic training

L Rissatto Sierra, G Fávaro, BR Cerri… - Microscopy …, 2018 - Wiley Online Library
The study aims to describe the tissue plasticity of MTJ through the morphological analysis of
MTJ soleus in ovariectomized aged female Wistar rats submitted to aquatic training. Forty …