A review of the pathways of human exposure to poly-and perfluoroalkyl substances (PFASs) and present understanding of health effects

EM Sunderland, XC Hu, C Dassuncao… - Journal of exposure …, 2019 - nature.com
Here, we review present understanding of sources and trends in human exposure to poly-
and perfluoroalkyl substances (PFASs) and epidemiologic evidence for impacts on cancer …

Perfluoroalkyl substances exposure and immunity, allergic response, infection, and asthma in children: review of epidemiologic studies

H von Holst, P Nayak, Z Dembek, S Buehler… - Heliyon, 2021 - cell.com
Background Increased exposure to perfluoroalkyl substances (PFAS) potentially affects
infant and childhood health through immunosuppression. Given rapidly evolving research …

[HTML][HTML] A systematic evidence map of chronic inflammation and immunosuppression related to per-and polyfluoroalkyl substance (PFAS) exposure

L Zhang, A Louie, G Rigutto, H Guo, Y Zhao, S Ahn… - Environmental …, 2023 - Elsevier
Background The ability to induce chronic inflammation and immunosuppression are two key
characteristics of carcinogens and important forms of immunotoxicity. The National …

Endocrine disruptor potential of short-and long-chain perfluoroalkyl substances (PFASs)—a synthesis of current knowledge with proposal of molecular mechanism

K Mokra - International journal of molecular sciences, 2021 - mdpi.com
Endocrine disruptors are a group of chemical compounds that, even in low concentrations,
cause a hormonal imbalance in the body, contributing to the development of various harmful …

Prenatal exposure to poly-and perfluoroalkyl substances and the incidence of asthma in early childhood

LM Zell-Baran, C Venter, D Dabelea, JM Norris… - Environmental …, 2023 - Elsevier
Exposure to poly and perfluoroalkyl substances (PFAS) in early life may increase the risk of
childhood asthma, but evidence has been inconsistent. We estimated associations between …

Perfluorooctane sulfonic acid disrupts protective tight junction proteins via protein kinase D in airway epithelial cells

JH Lucas, Q Wang, I Rahman - Toxicological Sciences, 2022 - academic.oup.com
Perfluorooctane sulfonic acid (PFOS) is a long chain per-and polyfluoroalklyl substance
(PFAS) that has been used in aqueous film-forming foams. Emerging epidemiological …

Asthma and Decreased Lung Function in Children Exposed to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs): An Updated Meta-Analysis Unveiling Research …

A Rafiee, S Faridi, PD Sly, L Stone, L Kennedy… - Environmental …, 2024 - Elsevier
Background and objective Associations between exposure to per-and polyfluoroalkyl
substances (PFAS) and pediatric asthma and reduced lung function in children are mixed …

Association between prenatal exposure to perfluoroalkyl substances and asthma in 5-year-old children in the Odense Child Cohort

IH Beck, CAG Timmermann, F Nielsen, G Schoeters… - Environmental …, 2019 - Springer
Background Asthma is the most common non-communicable disease in children. Prenatal
exposure to perfluoroalkyl substances (PFASs), a group of persistent environmental …

Per and poly-fluoroalkyl substances and respiratory health in an Inuit community

A Aker, Y Courtemanche, P Ayotte, P Robert… - Environmental …, 2024 - Springer
Concentrations of plasma per and poly-fluoroalkyl substances (PFAS) are elevated in the
Inuit population of Nunavik and may be causing adverse health effects. Respiratory health …

Effects of developmental exposure to perfluoroalkyl substances on health outcomes in pregnant women and offspring

H Goudarzi, K Yamazaki - Health Impacts of Developmental Exposure to …, 2020 - Springer
Perfluoroalkyl substances (PFASs) are highly stable and ubiquitous compounds which have
been used for more than 60 years in various products; however, their potential health effects …