Boosting the full potential of PyMOL with structural biology plugins

S Rosignoli, A Paiardini - Biomolecules, 2022 - mdpi.com
Over the past few decades, the number of available structural bioinformatics pipelines,
libraries, plugins, web resources and software has increased exponentially and become …

Quercetin: a potential polydynamic drug

N Georgiou, MG Kakava, EA Routsi, E Petsas… - Molecules, 2023 - mdpi.com
The study of natural products as potential drug leads has gained tremendous research
interest. Quercetin is one of those natural products. It belongs to the family of flavonoids and …

Anticancer therapeutic potential of genus Diospyros: From phytochemistry to clinical applications—A review

A Rauf, Z Akram, N Hafeez, AA Khalil… - Food Science & …, 2024 - Wiley Online Library
The genus Diospyros has gained significant attention in the scientific community owing to its
diverse bioactivities ascribed to specific bioactive constituents present in different species of …

Recognizing novel drugs against Keap1 in Alzheimer's disease using machine learning grounded computational studies

N Mukerjee, K Al-Khafaji, S Maitra… - Frontiers in Molecular …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common neurodegenerative disorder in the world,
affecting an estimated 50 million individuals. The nerve cells become impaired and die due …

Unveiling Nature's potential: promising natural compounds in Parkinson's disease management

CK Bhusal, DE Uti, D Mukherjee, T Alqahtani… - Parkinsonism & Related …, 2023 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the
progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta …

A Comparative Study of Diospyros malabarica (Gaub) Extracts in Various Polarity‐Dependent Solvents for Evaluation of Phytoconstituents and Biological Activities

Z Zreen, A Hameed, S Kiran, T Farooq… - BioMed Research …, 2022 - Wiley Online Library
Keeping in mind the ascribed repute of Diospyros malabarica (D. malabarica), this
investigation was commenced to assess the effect of diverse solvents on extraction yields …

Nanotechnological synergy of mangiferin and curcumin in modulating PI3K/Akt/mTOR pathway: a novel front in ovarian cancer precision therapeutics

HM Alharbi, T Alqahtani, AH Alamri… - Frontiers in …, 2024 - frontiersin.org
Background: Ovarian cancer, colloquially termed the “silent killer” among gynecological
malignancies, remains elusive due to its often-asymptomatic progression and diagnostic …

Synthesis and Evaluation of Biological Activities for a Novel 1, 2, 3, 4-Tetrahydroisoquinoline Conjugate with Dipeptide Derivatives: Insights from Molecular Docking …

SR Tivari, SV Kokate, JL Belmonte-Vázquez… - ACS …, 2023 - ACS Publications
Peptide synthesis has opened new frontiers in the quest for bioactive molecules with
limitless biological applications. This study presents the synthesis of a series of novel …

Potent hepatoprotective activity of common rattan (Calamus rotang L.) leaf extract and its molecular mechanism

WS Anwar, FM Abdel-Maksoud, AM Sayed… - … medicine and therapies, 2023 - Springer
Abstract Background Calamus rotang L.(CR) is an Indian shrub. The leaves and other
organs of the plant are traditionally used in India for treatment of various diseases. The in …

Diospyros malabarica Fruit Extract Derived Silver Nanoparticles: A Biocompatible Antibacterial Agent

SA Polash, A Hamza, MM Hossain… - Frontiers in …, 2022 - frontiersin.org
Biogenic silver nanoparticles demonstrate excellent antibacterial activity against a broad
range of bacteria. Herein, aqueous biogenic silver nanoparticles (Aq@ bAgNPs) and …