Dietary strategies for metabolic syndrome: a comprehensive review

S Castro-Barquero, AM Ruiz-León, M Sierra-Pérez… - Nutrients, 2020 - mdpi.com
Metabolic syndrome is a cluster of metabolic risk factors, characterized by abdominal
obesity, dyslipidemia, low levels of high-density lipoprotein cholesterol (HDL-c) …

Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management

B Misselwitz, M Butter, K Verbeke, MR Fox - Gut, 2019 - gut.bmj.com
Lactose is the main source of calories in milk, an essential nutriedigestion, patients with
visceral hypersensitivity nt in infancy and a key part of the diet in populations that maintain …

The effect of host genetics on the gut microbiome

MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic… - Nature …, 2016 - nature.com
The gut microbiome is affected by multiple factors, including genetics. In this study, we
assessed the influence of host genetics on microbial species, pathways and gene ontology …

Country, regional, and global estimates for lactose malabsorption in adults: a systematic review and meta-analysis

CL Storhaug, SK Fosse, LT Fadnes - The Lancet Gastroenterology & …, 2017 - thelancet.com
Background Studies have shown wide variation in the prevalence of lactose malabsorption
across the world, but no systematic reviews or meta-analyses have recently assessed the …

On the evolution of lactase persistence in humans

L Ségurel, C Bon - Annual review of genomics and human …, 2017 - annualreviews.org
Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in
frequency across human populations. This trait represents an adaptation to the …

Evolution of lactase persistence: an example of human niche construction

P Gerbault, A Liebert, Y Itan… - … of the Royal …, 2011 - royalsocietypublishing.org
Niche construction is the process by which organisms construct important components of
their local environment in ways that introduce novel selection pressures. Lactase …

The origins of lactase persistence in Europe

Y Itan, A Powell, MA Beaumont, J Burger… - PLoS computational …, 2009 - journals.plos.org
Lactase persistence (LP) is common among people of European ancestry, but with the
exception of some African, Middle Eastern and southern Asian groups, is rare or absent …

Tumor cell-derived exosomes: a message in a bottle

P Kharaziha, S Ceder, Q Li, T Panaretakis - Biochimica et Biophysica Acta …, 2012 - Elsevier
Exosomes constitute the newest mode of intercellular communication, transmitting
information between cells. This exchange of molecular information is facilitated by their …

Lactose intolerance: diagnosis, genetic, and clinical factors

R Mattar, DF de Campos Mazo… - Clinical and experimental …, 2012 - Taylor & Francis
Most people are born with the ability to digest lactose, the major carbohydrate in milk and
the main source of nutrition until weaning. Approximately 75% of the world's population …

Lactose digestion and the evolutionary genetics of lactase persistence

CJE Ingram, CA Mulcare, Y Itan, MG Thomas… - Human genetics, 2009 - Springer
It has been known for some 40 years that lactase production persists into adult life in some
people but not in others. However, the mechanism and evolutionary significance of this …