Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

The growing number of patients with obstructive sleep apnea is challenging healthcare
systems worldwide. Obstructive sleep apnea is characterized by chronic intermittent …

Failed proteostasis is a well-documented feature of Alzheimer's disease, particularly,
reduced protein degradation and clearance. However, the contribution of failed proteostasis …

Background Obstructive sleep apnea (OSA) is mainly characterized by sleep fragmentation
and chronic intermittent hypoxia (CIH), the latter one being associated with multiple organ …

Abstract Changes in sleep during mid-to-late life are associated with risk for Alzheimer's
disease (AD). Mechanistic understanding of this association necessitates measurement …

Medial temporal structures, namely the hippocampus, the entorhinal cortex and the
parahippocampal gyrus, are particularly vulnerable to Alzheimer's disease and hypoxemia …

Obstructive sleep apnea has been associated with cognitive impairment and may be linked
to disorders of cognitive function. These associations may be a result of intermittent …

To assess prefrontal brain network abnormality in adults with obstructive sleep apnea (OSA),
resting‐state functional near infrared spectroscopy (rs‐fNIRS) was used to evaluate 52 …

Across the lifespan, the human body and brain endure the impact of a plethora of
exogenous and endogenous factors that determine the health outcome in old age. The …

Background Alzheimer's disease (AD) is an irreversible, progressive brain disorder that
impairs memory, thinking, language, and, eventually, the ability to carry out the simplest of …