Hydrogels in a historical perspective: From simple networks to smart materials

SJ Buwalda, KWM Boere, PJ Dijkstra, J Feijen… - Journal of controlled …, 2014 - Elsevier
Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins

BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …

Cell protective, ABC triblock polymer-based thermoresponsive hydrogels with ROS-triggered degradation and drug release

MK Gupta, JR Martin, TA Werfel, T Shen… - Journal of the …, 2014 - ACS Publications
A combination of anionic and RAFT polymerization was used to synthesize an ABC triblock
polymer poly [(propylenesulfide)-block-(N, N-dimethylacrylamide)-block-(N …

Transiently thermoresponsive polymers and their applications in biomedicine

N Vanparijs, L Nuhn, BG De Geest - Chemical Society Reviews, 2017 - pubs.rsc.org
The focus of this review is on the class of transiently thermoresponsive polymers. These
polymers are thermoresponsive, but gradually lose this property upon chemical …

Injectable hydrogels

DJ Overstreet, D Dutta, SE Stabenfeldt… - Journal of Polymer …, 2012 - Wiley Online Library
Hydrogels are promising for a variety of medical applications due to their high water content
and mechanical similarity to natural tissues. When made injectable, hydrogels can reduce …

Engineering hyaluronic acid for the development of new treatment strategies for osteoarthritis

YS Kim, F Guilak - International journal of molecular sciences, 2022 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disease that is characterized by inflammation of
the joints, degradation of cartilage, and the remodeling of other joint tissues. Due to the …

PNIPAAm-based biohybrid injectable hydrogel for cardiac tissue engineering

A Navaei, D Truong, J Heffernan, J Cutts, D Brafman… - Acta biomaterialia, 2016 - Elsevier
Injectable biomaterials offer a non-invasive approach to deliver cells into the myocardial
infarct region to maintain a high level of cell retention and viability and initiate the …

Development and disassembly of single and multiple acid-cleavable block copolymer nanoassemblies for drug delivery

AM Jazani, JK Oh - Polymer Chemistry, 2020 - pubs.rsc.org
Drug delivery via block copolymer nanoassemblies has been widely viewed as an efficient
way to augment therapeutic efficiency of anticancer drugs for cancer therapy. Acid …

Differentiation of cardiosphere-derived cells into a mature cardiac lineage using biodegradable poly (N-isopropylacrylamide) hydrogels

Z Li, X Guo, S Matsushita, J Guan - Biomaterials, 2011 - Elsevier
A family of injectable and thermosensitive hydrogels suitable for myocardial injection was
developed to deliver cardiosphere-derived cells (CDCs), an emerging and promising cell …

Responsive nematic gels from the self-assembly of aqueous nanofibres

Z Huang, H Lee, E Lee, SK Kang, JM Nam… - Nature …, 2011 - nature.com
Aqueous nanofibres constructed by the self-assembly of small amphiphilic molecules can
become entangled to form hydrogels that have a variety of applications including tissue …