Hypoxia in lung cancer management: a translational approach

J Ancel, JM Perotin, M Dewolf, C Launois, P Mulette… - Cancers, 2021 - mdpi.com
Simple Summary Hypoxia is a common feature of lung cancers. Nonetheless, no guidelines
have been established to integrate hypoxia-associated biomarkers in patient management …

Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention

MR Jadus, J Natividad, A Mai, Y Ouyang… - Journal of …, 2012 - Wiley Online Library
Lung cancers remain one of the most common and deadly cancers in the world today
(12.5% of newly diagnosed cancers) despite current advances in chemo‐and radiation …

[HTML][HTML] Co-delivery of VEGF siRNA and etoposide for enhanced anti-angiogenesis and anti-proliferation effect via multi-functional nanoparticles for orthotopic non …

F Li, Y Wang, W Chen, D Wang, Y Zhou, B You… - Theranostics, 2019 - ncbi.nlm.nih.gov
Targeting tumor angiogenesis pathway via VEGF siRNA (siVEGF) has shown great potential
in treating highly malignant and metastatic non-small cell lung cancer (NSCLC). However …

[HTML][HTML] Polymorphisms in VEGF and IL-8 predict tumor recurrence in stage III colon cancer

G Lurje, W Zhang, AM Schultheis, D Yang, S Groshen… - Annals of …, 2008 - Elsevier
Background Identifying molecular markers for tumor recurrence is critical in successfully
selecting patients with stage III colon cancer who are more likely to benefit from adjuvant …

Vascular endothelial growth factor gene polymorphisms associated with prognosis for patients with colorectal cancer

JG Kim, YS Chae, SK Sohn, YY Cho, JH Moon… - Clinical Cancer …, 2008 - AACR
Purpose: Vascular endothelial growth factor (VEGF) or its family may be considered to play
an important role in lymphangiogenesis and lymphatic tumor spread, thereby affecting …

Caspase 9 promoter polymorphisms and risk of primary lung cancer

JY Park, JM Park, JS Jang, JE Choi… - Human molecular …, 2006 - academic.oup.com
Abstract Caspase-9 (CASP-9) is an initiator CASP in the apoptosome-driven apoptosis
pathway and plays an important role in the development and progression of cancer …

Genotypes and haplotypes of the VEGF gene are associated with higher mortality and lower VEGF plasma levels in patients with ARDS

R Zhai, MN Gong, W Zhou, TB Thompson, P Kraft, L Su… - Thorax, 2007 - thorax.bmj.com
Background: Endothelial injury is an important prognostic factor in acute respiratory distress
syndrome (ARDS). Vascular endothelial growth factor (VEGF) plays a critical role in …

Association of VEGF genetic polymorphisms with prostate carcinoma risk and clinical outcome

S Sfar, E Hassen, H Saad, F Mosbah, L Chouchane - Cytokine, 2006 - Elsevier
Objectives: Vascular endothelial growth factor (VEGF) is a potent stimulus of angiogenesis
that has an important role in many human malignancies including prostate carcinoma (PCa) …

Prospective analysis of the impact of VEGF‐A gene polymorphisms on the pharmacodynamics of bevacizumab‐based therapy in metastatic breast cancer patients

MC Etienne‐Grimaldi, P Formento… - British journal of …, 2011 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• Functional polymorphisms on the
VEGF‐A gene, known to be linked to cancer risk or to VEGF‐A plasma concentrations, have …

Single nucleotide polymorphisms and mRNA expression of VEGF-A in papillary thyroid carcinoma: potential markers for aggressive phenotypes

A Salajegheh, RA Smith, K Kasem, V Gopalan… - European Journal of …, 2011 - Elsevier
BACKGROUND AND OBJECTIVES: Polymorphisms of the VEGF gene are known to affect
the biological behaviour of cancers but have seldom been studied in thyroid cancer. The aim …