Acetaminophen (APAP) is the most common prescription medicine around the world for the
treatment of pain and fever and is considered to be a safe drug at its therapeutic dose …

The role of gut microbiome in human health and disease is well established. While evidence-
based pharmacological studies utilize a variety of chemical-induced metabolic and …

The co-existence of microplastics (MPs) and antibiotics in the coastal environment poses a
combined ecological risk. Single toxic effects of MPs or antibiotics on aquatic organisms …

The rising incidence of drug-induced liver injury (DILI) parallels contemporary dietary shifts
that have transformed the composition of human gut microbiota. The relationship between …

Irritable bowel syndrome is a chronic disorder affecting the gastrointestinal tract, negatively
impacting patients' quality of life. Here, we aimed to evaluate the effects of Lacticaseibacillus …

Background The gut microbiome is a diverse system within the gastrointestinal tract
composed of trillions of microorganisms (gut microbiota), along with their genomes …

The mammalian gut microbiota plays diverse and essential roles in modulating host
physiology. Key mediators determining the outcome of the microbiota-host interactions are …

Chronic kidney disease (CKD) affects approximately 12% of the global population, posing a
significant health threat. Inflammation plays a crucial role in the uremic phenotype of non …

Acetaminophen (APAP) intoxication is the foremost cause of drug-induced liver failure in
developed countries. The only pharmacologic treatment option, N-acetylcysteine (NAC), is …

Nonalcoholic fatty liver disease (NAFLD) poses a great global challenge to public health, yet
it holds promise for amelioration through plant-derived polysaccharide. Ginkgo biloba seeds …