Advantages and limitations of commonly used methods to assay the molecular permeability of gap junctional intercellular communication

M Abbaci, M Barberi-Heyob, W Blondel… - …, 2008 - Taylor & Francis
The role of gap junctional intercellular communication (GJIC) in regulation of normal growth
and differentiation is becoming increasingly recognized as a major cellular function. GJIC …

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1

JM Rhett, J Jourdan, RG Gourdie - Molecular biology of the cell, 2011 - Am Soc Cell Biol
Connexin 43 (Cx43) is a gap junction (GJ) protein widely expressed in mammalian tissues
that mediates cell-to-cell coupling. Intercellular channels comprising GJ aggregates form …

Multiphoton intravital microscopy of rodents

CLGJ Scheele, D Herrmann, E Yamashita… - Nature Reviews …, 2022 - nature.com
Tissues are heterogeneous with respect to cellular and non-cellular components and in the
dynamic interactions between these elements. To study the behaviour and fate of individual …

[HTML][HTML] The mechanism of selenium regulating the permeability of vascular endothelial cells through selenoprotein O

J Wu, Y Zhang, T Liu, J Yang, X Sun, X Gao - Redox biology, 2024 - Elsevier
Vascular diseases, a leading cause of death in human, are strongly associated with
pathological damage to blood vessels. The selenoprotein (Sel) have been reported to play …

Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes

DM Pedrotty, RY Klinger, RD Kirkton… - Cardiovascular …, 2009 - academic.oup.com
Aims The pathological proliferation of cardiac fibroblasts (CFs) in response to heart injury
results in fibrosis, which correlates with arrhythmia generation and heart failure. Here we …

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes.

T Martins-Marques, S Catarino, M Zuzarte… - Biochemical …, 2015 - portlandpress.com
Moreover, we establish that degradation of Cx43 in ischaemia or I/R (ischaemia/reperfusion)
relies upon different molecular players. Indeed, degradation of Cx43 during early periods of …

Fibrinogen improves liver function via promoting cell aggregation and fibronectin assembly in hepatic spheroids

R Li, J Liu, J Ma, X Sun, Y Wang, J Yan, Q Yu, J Diao… - Biomaterials, 2022 - Elsevier
Many key functions performed by the liver depend on the interaction between parenchymal
cells and the microenvironment comprised of neighboring cells and extracellular matrix. The …

Nedd4-2-dependent regulation of astrocytic Kir4. 1 and Connexin43 controls neuronal network activity

B Altas, HJ Rhee, A Ju, HC Solís, S Karaca… - Journal of Cell …, 2024 - rupress.org
Nedd4-2 is an E3 ubiquitin ligase in which missense mutation is related to familial epilepsy,
indicating its critical role in regulating neuronal network activity. However, Nedd4-2 …

Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies

RD Kirkton, N Bursac - Nature communications, 2011 - nature.com
Patch-clamp recordings in single-cell expression systems have been traditionally used to
study the function of ion channels. However, this experimental setting does not enable …

The effect of 3-hydroxybutyrate methyl ester on learning and memory in mice

XH Zou, HM Li, S Wang, M Leski, YC Yao, XD Yang… - Biomaterials, 2009 - Elsevier
Learning and memory requires energy-demanding cellular processes and can be enhanced
when the brain is supplemented with metabolic substrates. In this study, we found that …