To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …

Highlights•Thymoquinone is a natural product with anticancer activity.•Thymoquinone can
methylate or demethylate DNA.•Thymoquinone can interfere with the histone acetylation …

Cancer is a global disease involving transformation of normal cells into tumor types via
numerous mechanisms, with mortality among all generations, in spite of the breakthroughs …

Thymoquinone (TQ) a plant-derived dietary of Nigella sativa, is a well-known traditionally
and clinically used natural medicine. The diverse pharmacological properties of TQ have …

Hepatocellular carcinoma (HCC) is characterized by its high vascularity and metastasis.
Thymoquinone (TQ), the main bio-active constituent of Nigella sativa, has shown anticancer …

Autoimmune diseases (AUDs) are a multifactorial disease, among which rheumatoid
arthritis, systemic lupus erythematosus and multiple sclerosis are more prevalent. Several …

Cancer, a major challenge to global health and healthcare systems, requires the study of
alternative and supportive treatments due to the limitations of conventional therapies. This …

The higher utilization of fruits and vegetables is well known to cure human maladies due to
the presence of bioactive components. Among these compounds, thymoquinone, a …

The drugs used to treat cancer not only kill fast-growing cancer cells, but also kill or slow the
growth of healthy cells, causing systemic toxicities that lead to altered functioning of normal …

In breast cancer, there has been evidence of atypical activation of signal transduction and
activators of transcription 3 (STAT3). Thymoquinone (TQ) exerts its anti‐neoplastic effect …