A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia

Z Dong, H Sepulveda, LJA Vazquez, C Blouin… - bioRxiv, 2024 - biorxiv.org
ASXL1 is one of the three most frequently mutated genes in age-related clonal
hematopoiesis (CH), with the others being DNMT3A and TET2. CH can progress to myeloid …