The identification and production of recombinant morphogens and growth factors that play key roles in tissue regeneration have generated much enthusiasm and numerous clinical …
A Beenken, M Mohammadi - Nature reviews Drug discovery, 2009 - nature.com
The family of fibroblast growth factors (FGFs) regulates a plethora of developmental processes, including brain patterning, branching morphogenesis and limb development …
R Censi, P Di Martino, T Vermonden… - Journal of Controlled …, 2012 - Elsevier
Tissue defects caused by diseases or trauma present enormous challenges in regenerative medicine. Recently, a better understanding of the biological processes underlying tissue …
CM Teven, EM Farina, J Rivas, RR Reid - Genes & diseases, 2014 - Elsevier
Fibroblast growth factors (FGF) and their receptors serve many functions in both the developing and adult organism. Humans contain 18 FGF ligands and four FGF receptors …
The role of preexisting collateral channels in the heart is far less well established. Early studies failed to show the existence of coronary-to-coronary artery connection in normal …
This review provides an overview of the incorporation of heparin into biomaterials with a focus on drug delivery and the use of heparin-based biomaterials for self-assembly of …
Despite extensive research, pro-angiogenic drugs have failed to translate clinically, and therapeutic angiogenesis, which has potential in the treatment of various cardiovascular …
M Simons, JA Ware - Nature reviews Drug discovery, 2003 - nature.com
Despite considerable progress in the management of ischaemic cardiovascular disease during the past three decades, there remains a significant population of patients who are not …