Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn

BH Majed, RA Khalil - Pharmacological reviews, 2012 - ASPET
Prostacyclin (PGI2) is a member of the prostanoid group of eicosanoids that regulate
homeostasis, hemostasis, smooth muscle function and inflammation. Prostanoids are …

Pathophysiology of reperfusion injury

P Cowled, R Fitridge - Mechanisms of Vascular Disease: A Textbook for …, 2020 - Springer
Abstract Ischaemia-Reperfusion Injury (IRI), which is often referred to as Reperfusion Injury
is the tissue damage that occurs following the return of blood flow to ischaemic tissues …

[HTML][HTML] Editor's choice–European Society for Vascular Surgery (ESVS) 2020 clinical practice guidelines on the management of acute limb ischaemia

M Björck, JJ Earnshaw, S Acosta, FB Gonçalves… - European Journal of …, 2020 - Elsevier
1.1. Purpose The European Society for Vascular Surgery (ESVS) has developed guidelines
for treating patients with acute limb ischaemia (ALI). The focus on the guidelines is on lower …

[HTML][HTML] Safety and efficacy of vacuum assisted thrombo-aspiration in patients with acute lower limb ischaemia: the INDIAN trial

G de Donato, E Pasqui, M Sponza, F Intrieri… - European Journal of …, 2021 - Elsevier
Objective The aim was to evaluate the short term safety and effectiveness of the
Penumbra/Indigo aspiration thrombectomy Systems (Penumbra Inc.) in patients with acute …

The relation between neutrophil/lymphocyte and platelet/lymphocyte ratios with mortality and limb amputation after acute limb ischaemia

E Pasqui, G de Donato, G Giannace, C Panzano… - …, 2022 - journals.sagepub.com
Objective Acute limb ischaemia is still considered a significant event, with considerable early-
and long-term amputation and mortality risk. Our study aims to investigate the predictive role …

[HTML][HTML] Long-term clinical results after iloprost treatment for bone marrow edema and avascular necrosis

T Claßen, A Becker, S Landgraeber… - Orthopedic …, 2016 - ncbi.nlm.nih.gov
The treatments of avascular osteonecrosis (AVN) include both conservative and surgical
methods which are dependent on the stage and progression of the disease. The vasoactive …

Acute on chronic limb ischemia: From surgical embolectomy and thrombolysis to endovascular options

G de Donato, E Pasqui, F Setacci, G Palasciano… - Seminars in vascular …, 2018 - Elsevier
After the invention of the balloon catheter by Fogarty in 1963, surgical thromboembolectomy
was considered the gold standard treatment for many years in patients with acute lower limb …

Compartment syndrome in the setting of vascular injury

TJ Percival, JM White, MA Ricci - Perspectives in vascular …, 2011 - journals.sagepub.com
Compartment syndrome after extremity vascular injury has gained attention with the current
conflicts in Iraq and Afghanistan. Compartment syndrome after extremity vascular injury is …

Evaluation of clinical outcomes after revascularization in patients with chronic limb-threatening ischemia: results from a prospective national cohort study …

G de Donato, F Benedetto, F Stilo, R Chiesa… - …, 2021 - journals.sagepub.com
We evaluated the outcomes of revascularization in patients with chronic limb-threatening
ischemia (CLTI) treated in real-world settings. This is a prospective multicenter cohort study …

Prostanoids in patients with peripheral arterial disease: a meta-analysis of placebo-controlled randomized clinical trials

V Vitale, M Monami, E Mannucci - Journal of Diabetes and its …, 2016 - Elsevier
Aims Prostanoids are indicated in the treatment of peripheral arterial disease (PAD).
Available trials suggest that these compounds could reduce the symptoms of intermittent …