Overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors

NA Ratcliffe, JP Furtado Pacheco, P Dyson… - Parasites & vectors, 2022 - Springer
This article presents an overview of paratransgenesis as a strategy to control pathogen
transmission by insect vectors. It first briefly summarises some of the disease-causing …

Interventions for the control of Crimean-Congo hemorrhagic fever and tick vectors

J de la Fuente, S Ghosh, L Lempereur, A Garrison… - npj Vaccines, 2024 - nature.com
Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic disease associated with its
principal tick vector, Hyalomma spp. with increasing fatal incidence worldwide. Accordingly …

Rodents as vehicle for delivery of transgenic bacteria to make paratransgenic sand fly vectors of cutaneous leishmaniasis in field condition

M Ghassemi, AA Akhavan, A Zahraei-Ramazani… - Scientific Reports, 2023 - nature.com
Vector-borne diseases, among them leishmaniasis, cause more than 700,000 deaths
annually. The lack of an effective vaccination and the increasing resistance of sand flies to …

[HTML][HTML] Innovative approaches for the control of ticks and tick-borne diseases

J de la Fuente, L Mazuecos, M Contreras - Ticks and Tick-Borne Diseases, 2023 - Elsevier
Ticks and tick-borne diseases constitute a major threat for human and animal health
worldwide. Vaccines for the control of tick infestations and transmitted pathogens still …

Engineering insects from the endosymbiont out

KM Elston, SP Leonard, P Geng, SB Bialik… - Trends in …, 2022 - cell.com
Insects are an incredibly diverse group of animals with species that benefit and harm natural
ecosystems, agriculture, and human health. Many insects have consequential associations …

[HTML][HTML] Frankenbacteriosis targeting interactions between pathogen and symbiont to control infection in the tick vector

L Mazuecos, P Alberdi, A Hernández-Jarguín… - Iscience, 2023 - cell.com
Tick microbiota can be targeted for the control of tick-borne diseases such as human
granulocytic anaplasmosis (HGA) caused by model pathogen, Anaplasma …

Naturally occurring microbiota associated with mosquito breeding habitats and their effects on mosquito larvae

HAK Ranasinghe… - BioMed research …, 2020 - Wiley Online Library
Immature mosquitoes are aquatic, and their distribution, abundance, and individual fitness in
a particular breeding habitat are known to be dependent on mainly three factors: biotic …

Dynamic of Composition and Diversity of Gut Microbiota in Triatoma rubrofasciata in Different Developmental Stages and Environmental Conditions

Y Hu, H Xie, M Gao, P Huang, H Zhou, Y Ma… - Frontiers in cellular …, 2020 - frontiersin.org
Triatoma rubrofasciata (T. rubrofasciata), one kind of triatomine insects, is the vector of
Trypanosoma cruzi (T. cruzi), which lead to American trypanosomiasis. Although the gut …

Altered Gut Microbiota and Immunity Defines Plasmodium vivax Survival in Anopheles stephensi

P Sharma, J Rani, C Chauhan, S Kumari… - Frontiers in …, 2020 - frontiersin.org
Blood-feeding enriched gut-microbiota boosts mosquitoes' anti-Plasmodium immunity. Here,
we ask how Plasmodium vivax alters gut-microbiota, anti-Plasmodial immunity, and impacts …

Comparative analysis of the gut microbiota of sand fly vectors of zoonotic visceral leishmaniasis (ZVL) in Iran; host-environment interplay shapes diversity

F Karimian, M Koosha, N Choubdar… - PLoS Neglected …, 2022 - journals.plos.org
The development of Leishmania parasites within sand fly vectors occurs entirely in the insect
gut lumen, in the presence of symbiotic and commensal bacteria. The impacts of host …