The tendon, as a compact connective tissue, is difficult to treat after an acute laceration or chronic degeneration. Gene-based therapy is a highly efficient strategy for diverse diseases …
T Tozaki, A Ohnuma, S Iwai, M Kikuchi… - Analytical …, 2021 - ACS Publications
Gene doping is banned in human sports, horseracing, and equestrian sports. One possible form of gene doping is to administer exogenous genes, called transgenes. Several …
T Tozaki, A Ohnuma, M Kikuchi, T Ishige… - Animal …, 2022 - Wiley Online Library
Processed pseudogenes, also known as retrocopy genes, are copies of messenger RNAs that have been reverse transcribed into DNA and inserted into the genome. In this study, we …
T Taguchi, M Lopez, C Takawira - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Background: Tendon healing is frequently prolonged, unpredictable, and results in poor tissue quality. Neotissue formed by adult multipotent stromal cells has the potential to guide …
J Haughan, KF Ortved… - Drug testing and analysis, 2023 - Wiley Online Library
Gene therapy uses genetic modification of cells to produce a therapeutic effect. Defective or missing genes can be repaired or replaced, or gene expression can be modified using a …
Gene doping, the use of gene therapy or genetic manipulation to enhance athletic performance, has emerged as a potential threat to the integrity and welfare of equine sports …
R Furukawa, T Tozaki, M Kikuchi… - Drug Testing and …, 2024 - Wiley Online Library
Gene doping is prohibited in horse sports and can involve the administration of exogenous genes, called transgenes, to postnatal animals. Quantitative polymerase chain reaction …
Gene therapy focuses on the genetic modification of cells, to produce a therapeutic effect or for the treatment of disease, by repairing or reconstructing defective genetic material. The …
J Liu, Z Zhao, Z Deng, X Chen, W Li - Pathology-Research and Practice, 2023 - Elsevier
It has been reported that tendon-derived stem cells (TDSCs) conduce to the ostosis in tendon diseases, and the molecular mechanism needs to be discussed. To investigate the …