Hairy root research: recent scenario and exciting prospects

S Guillon, J Tremouillaux-Guiller, PK Pati… - Current opinion in plant …, 2006 - Elsevier
High stability of the production of secondary metabolites is an interesting characteristic of
hairy root cultures. For 25 years, hairy roots have been investigated as a biological system …

Hairy root culture technology: applications, constraints and prospect

S Gantait, E Mukherjee - Applied Microbiology and Biotechnology, 2021 - Springer
Hairy root (HR) culture, a successful biotechnology combining in vitro tissue culture with
recombinant DNA machinery, is intended for the genetic improvement of plants. This …

Harnessing the potential of hairy roots: dawn of a new era

S Guillon, J Trémouillaux-Guiller, PK Pati… - TRENDS in …, 2006 - cell.com
In the past two decades, hairy root research for the production of important secondary
metabolites has received a lot of attention. The addition of knowledge to overcome the …

Berberine induces apoptotic cell death via activation of caspase-3 and-8 in HL-60 human leukemia cells: nuclear localization and structure–activity relationships

S Okubo, T Uto, A Goto, H Tanaka… - The American Journal …, 2017 - World Scientific
Berberine (BBR), an isoquinoline alkaloid, is a well-known bioactive compound contained in
medicinal plants used in traditional and folk medicines. In this study, we investigated the …

Hairy roots, their multiple applications and recent patents

M A. Talano, A Laura Wevar Oller… - Recent patents on …, 2012 - benthamdirect.com
In the last years, hairy root (HR) cultures are gaining attention in the biotechnology industry.
This particular plant cell culture derives from explants infected with Agrobacterium …

Hairy roots: an ideal platform for transgenic plant production and other promising applications

AB Makhzoum, P Sharma, MA Bernards… - … , plant growth, and the …, 2013 - Springer
The infection of plants by Agrobacterium rhizogenes results in a “hairy root” phenotype
characterized by rapid growth in hormone-free medium, an unusual ageotropism and …

Antibodies from plants for bionanomaterials

G Edgue, RM Twyman, V Beiss… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Antibodies are produced as part of the vertebrate adaptive immune response and are not
naturally made by plants. However, antibody DNA sequences can be introduced into plants …

Hairy root cultures: a novel way to mass produce plant secondary metabolites

J Shilpha, MJV Largia, RR Kumar, L Satish… - … plant metabolomics and …, 2023 - Springer
The in vitro method of transformation of root cultures using natural soil-borne bacterium
Rhizobium rhizogenes (earlier known as Agrobacterium rhizogenes) is considered as a …

The current status and future applications of hairy root cultures

N Dhiman, V Patial, A Bhattacharya - Biotechnological Approaches for …, 2018 - Springer
Hairy roots are produced when the soil phytopathogen, Agrobacterium rhizogenes, infects a
host plant. Just like normal roots, the hairy roots have the capacity to absorb target elements …

Monoclonal antibodies and immunoassay for medical plant-derived natural products: a review

X Yan, Y Zhao, Y Zhang, H Qu - Molecules, 2017 - mdpi.com
Owing to the widespread application value, monoclonal antibodies (MAbs) have become a
tool of increasing importance in modern bioscience research since their emergence …