Benzydamine is a non-steroidal anti-inflammatory drug with distinct pharmacological
properties from other compounds in the same therapeutic class. The differences are …

Background Schizophrenia is a serious long-term psychotic disorder marked by positive and
negative symptoms, severe behavioral problems and cognitive function deficits. The cause …

Antipsychotic effects seem to decrease in relapsed schizophrenia patients and the
underlying mechanisms remain to be elucidated. Based on the essential role of …

Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids
(PUFAs) in early psychosis. The present study investigates the molecular mechanism of …

Objectives Understanding the biological process and progression of schizophrenia is the
first step to developing novel approaches and new interventions. Research on new …

Objective Immune system dysregulation is hypothesised to be central to the
aetiopathogenesis of schizophrenia; however, the role of sterile inflammation remains …

Membrane phospholipid deficits have been well-documented in schizophrenia (SZ) patients.
Free fatty acids (FFAs) partially come from the hydrolysis of membrane phospholipids and …

Evidence indicates that abnormal phospholipase A2 (PLA2) levels and niacin insensitivity
are present in individuals with schizophrenia. This study was designed to determine whether …

The cellular and molecular mechanisms underlying onset and development of
schizophrenia have not yet been completely elucidated, but the association of disturbed …

In this review paper, we present current theories about the inflammatory etiopathogenesis of
schizophrenia. We mentioned the biopsychosocial etiological model of the disease and …