Pharmacogenetics to guide cardiovascular drug therapy

JD Duarte, LH Cavallari - Nature Reviews Cardiology, 2021 - nature.com
Over the past decade, pharmacogenetic testing has emerged in clinical practice to guide
selected cardiovascular therapies. The most common implementation in practice is …

Advancing pharmacogenomics from single-gene to preemptive testing

CE Haidar, KR Crews, JM Hoffman… - Annual review of …, 2022 - annualreviews.org
Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

Implementation of preemptive DNA sequence–based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study

L Wang, SE Scherer, SJ Bielinski, DM Muzny… - Genetics in …, 2022 - Elsevier
Abstract Purpose The Mayo-Baylor RIGHT 10K Study enabled preemptive, sequence-based
pharmacogenomics (PGx)-driven drug prescribing practices in routine clinical care within a …

Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing

JD Duarte, R Dalton, AL Elchynski, DM Smith… - Genetics in …, 2021 - nature.com
Purpose The increased availability of clinical pharmacogenetic (PGx) guidelines and
decreasing costs for genetic testing have slowly led to increased utilization of PGx testing in …

Reimbursement of pharmacogenetic tests at a tertiary academic medical center in the United States

LK Lemke, B Alam, R Williams, P Starostik… - Frontiers in …, 2023 - frontiersin.org
Introduction: Pharmacogenetics (PGx) has the potential to improve health outcomes but cost
of testing is a barrier for equitable access. Reimbursement by insurance providers may …

Applications for pharmacogenomics in pharmacy practice: A scoping review

M Hayashi, DA Hamdy, SH Mahmoud - Research in Social and …, 2022 - Elsevier
Abstract Background Pharmacogenomics (PGx) can provide valuable pharmacokinetic and
pharmacodynamic information for the pharmacist's assessment of drug therapy, especially …

Design and early implementation successes and challenges of a pharmacogenetics consult clinic

MJ Arwood, EA Dietrich, BQ Duong, DM Smith… - Journal of clinical …, 2020 - mdpi.com
Pharmacogenetic testing (PGT) is increasingly being used as a tool to guide clinical
decisions. This article describes the development of an outpatient, pharmacist-led …

Characterizing pharmacogenetic programs using the consolidated framework for implementation research: A structured scoping review

JH McDermott, S Wright, V Sharma… - Frontiers in …, 2022 - frontiersin.org
Several healthcare organizations have developed pre-emptive pharmacogenetic testing
programs, where testing is undertaken prior to the prescription of a medicine. This review …

Strategies and settings of clinical pharmacogenetic implementation: a scoping review of pharmacogenetics programs

T Luczak, SJ Brown, D Armbruster… - …, 2021 - Taylor & Francis
Pharmacogenetic (PGx) literature has shown beneficial outcomes in safety, efficacy and cost
when evidence-based gene-drug decision making is incorporated into clinical practice. PGx …

[HTML][HTML] Receptor Pharmacogenomics: Deciphering Genetic Influence on Drug Response

SA Anghel, CE Dinu-Pirvu, MA Costache… - International Journal of …, 2024 - mdpi.com
The paradigm “one drug fits all” or “one dose fits all” will soon be challenged by
pharmacogenetics research and application. Drug response—efficacy or safety—depends …